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[KO Validated] DDIT4 Rabbit pAb

Human, Mouse, Rat
WB (Homo sapiens, Mus musculus)
Q9NX09
$477/ 100 µl
Quantity
Total: $477

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5516530
TypePolyclonal Antibodies
HostRabbit
Positive controlA-549, DU145, U-251MG
IsotypeIgG
SummaryRegulates cell growth, proliferation and survival via inhibition of the activity of the mammalian target of rapamycin complex 1 (mTORC1. Inhibition of mTORC1 is mediated by a pathway that involves DDIT4/REDD1, AKT1, the TSC1-TSC2 complex and the GTPase RHEB. Plays an important role in responses to cellular energy levels and cellular stress, including responses to hypoxia and DNA damage. Regulates p53/TP53-mediated apoptosis in response to DNA damage via its effect on mTORC1 activity. Its role in the response to hypoxia depends on the cell type; it mediates mTORC1 inhibition in fibroblasts and thymocytes, but not in hepatocytes (By similarity. Required for mTORC1-mediated defense against viral protein synthesis and virus replication (By similarity. Inhibits neuronal differentiation and neurite outgrowth mediated by NGF via its effect on mTORC1 activity. Required for normal neuron migration during embryonic brain development. Plays a role in neuronal cell death.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price477$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-232 of human DDIT4 (NP_061931.1).
PurificationAffinity purification
Gene ID54541
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IF 1:50 - 1:200

All Names

AlternameDDIT4; Dig2; REDD-1; REDD1

Conjugated Antibody

This product is also available conjugated. Format: E45R27947N-Conjugate. Price: $485 / Size: 100μl.

E45R27947N-FITC$485 / 100μlE45R27947N-Biotin$485 / 100μlE45R27947N-HRP$485 / 100μlE45R27947N-AP$485 / 100μlE45R27947N-AF350$485 / 100μlE45R27947N-AF405M$485 / 100μlE45R27947N-AF488$485 / 100μlE45R27947N-AF514$485 / 100μlE45R27947N-AF532$485 / 100μlE45R27947N-AF555$485 / 100μlE45R27947N-AF568$485 / 100μlE45R27947N-AF405S$485 / 100μlE45R27947N-AF405L$485 / 100μlE45R27947N-AF546$485 / 100μlE45R27947N-AF594$485 / 100μlE45R27947N-AF610$485 / 100μlE45R27947N-AF635$485 / 100μlE45R27947N-AF647$485 / 100μlE45R27947N-AF680$485 / 100μlE45R27947N-AF700$485 / 100μlE45R27947N-AF750$485 / 100μlE45R27947N-AF790$485 / 100μlE45R27947N-APC$485 / 100μlE45R27947N-PE$485 / 100μlE45R27947N-Cy3$485 / 100μlE45R27947N-Cy5$485 / 100μlE45R27947N-Cy5.5$485 / 100μlE45R27947N-Cy7$485 / 100μlE45R27947N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

[KO Validated] DDIT4 Rabbit pAb | EnoGene Biotech Co. Ltd