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FBXW7 Rabbit pAb

Human, Mouse, Rat
WB (BGC823, Homo sapiens, Mus musculus)
IF (Mus musculus)
Q969H0
$409/ 100 µl
Quantity
Total: $409

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5505748
TypePolyclonal Antibodies
HostRabbit
Positive controlSH-SY5Y, Mouse testis, Rat heart
IsotypeIgG
SummaryThis gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene was previously referred to as FBX30, and belongs to the Fbws class; in addition to an F-box, this protein contains 7 tandem WD40 repeats. This protein binds directly to cyclin E and probably targets cyclin E for ubiquitin-mediated degradation. Mutations in this gene are detected in ovarian and breast cancer cell lines, implicating the gene's potential role in the pathogenesis of human cancers. Multiple transcript variants encoding different isoforms have been found for this gene.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 408-707 of human FBXW7 (NP_361014.1).
PurificationAffinity purification
Gene ID55294
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200

All Names

AlternameFBXW7; AGO; CDC4; FBW6; FBW7; FBX30; FBXO30; FBXW6; SEL-10; SEL10; hAgo; hCdc4

Conjugated Antibody

This product is also available conjugated. Format: E45R26174N-Conjugate. Price: $485 / Size: 100μl.

E45R26174N-FITC$485 / 100μlE45R26174N-Biotin$485 / 100μlE45R26174N-HRP$485 / 100μlE45R26174N-AP$485 / 100μlE45R26174N-AF350$485 / 100μlE45R26174N-AF405M$485 / 100μlE45R26174N-AF488$485 / 100μlE45R26174N-AF514$485 / 100μlE45R26174N-AF532$485 / 100μlE45R26174N-AF555$485 / 100μlE45R26174N-AF568$485 / 100μlE45R26174N-AF405S$485 / 100μlE45R26174N-AF405L$485 / 100μlE45R26174N-AF546$485 / 100μlE45R26174N-AF594$485 / 100μlE45R26174N-AF610$485 / 100μlE45R26174N-AF635$485 / 100μlE45R26174N-AF647$485 / 100μlE45R26174N-AF680$485 / 100μlE45R26174N-AF700$485 / 100μlE45R26174N-AF750$485 / 100μlE45R26174N-AF790$485 / 100μlE45R26174N-APC$485 / 100μlE45R26174N-PE$485 / 100μlE45R26174N-Cy3$485 / 100μlE45R26174N-Cy5$485 / 100μlE45R26174N-Cy5.5$485 / 100μlE45R26174N-Cy7$485 / 100μlE45R26174N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

FBXW7 Rabbit pAb | EnoGene Biotech Co. Ltd