Product Information
Cite ID#EN5516665
TypePolyclonal Antibodies
HostRabbit
Positive controlMCF7, HeLa, 293T, HepG2, Mouse spleen, Mouse thymus, Mouse lung, Mouse heart, Mouse liver
IsotypeIgG
SummaryThis gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.