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NLRP3 Rabbit pAb
Human, Mouse, Rat
WB (Mus musculus, Rattus norvegicus, Homo sapiens, Danio rerio)
IHC (Mus musculus, Homo sapiens)
IF (Mus musculus)
IHC (Mus musculus, Homo sapiens)
IF (Mus musculus)
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5516576
TypePolyclonal Antibodies
HostRabbit
Positive control293T, Rat lung
IsotypeIgG
SummaryThis gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are suggested by available data; however, insufficient evidence is available to determine if all of the represented 5' UTR splice patterns are biologically valid.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant protein of human NLRP3
PurificationAffinity purification
Gene ID114548
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
IHC 1:50 - 1:200
IF 1:50 - 1:200
All Names
AlternameNLRP3; AGTAVPRL; AII; AVP; C1orf7; CIAS1; CLR1.1; FCAS; FCAS1; FCU; MWS; NALP3; PYPAF1
Conjugated Antibody
This product is also available conjugated. Format: E45R25982N-Conjugate. Price: $485 / Size: 100μl.
E45R25982N-FITC$485 / 100μlE45R25982N-Biotin$485 / 100μlE45R25982N-HRP$485 / 100μlE45R25982N-AP$485 / 100μlE45R25982N-AF350$485 / 100μlE45R25982N-AF405M$485 / 100μlE45R25982N-AF488$485 / 100μlE45R25982N-AF514$485 / 100μlE45R25982N-AF532$485 / 100μlE45R25982N-AF555$485 / 100μlE45R25982N-AF568$485 / 100μlE45R25982N-AF405S$485 / 100μlE45R25982N-AF405L$485 / 100μlE45R25982N-AF546$485 / 100μlE45R25982N-AF594$485 / 100μlE45R25982N-AF610$485 / 100μlE45R25982N-AF635$485 / 100μlE45R25982N-AF647$485 / 100μlE45R25982N-AF680$485 / 100μlE45R25982N-AF700$485 / 100μlE45R25982N-AF750$485 / 100μlE45R25982N-AF790$485 / 100μlE45R25982N-APC$485 / 100μlE45R25982N-PE$485 / 100μlE45R25982N-Cy3$485 / 100μlE45R25982N-Cy5$485 / 100μlE45R25982N-Cy5.5$485 / 100μlE45R25982N-Cy7$485 / 100μlE45R25982N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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