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IFIT3 Rabbit pAb

E45R25357NDatasheetCOAMSDS
Human, Mouse, Rat
IHC (Rattus norvegicus)
WB (Mus musculus)
O14879
$409/ 100 µl
Quantity
Total: $409

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5505702
TypePolyclonal Antibodies
HostRabbit
Positive controlMouse kidney, Rat liver
IsotypeIgG
SummaryIFN-induced antiviral protein which acts as an inhibitor of cellular as well as viral processes, cell migration, proliferation, signaling, and viral replication. Enhances MAVS-mediated host antiviral responses by serving as an adapter bridging TBK1 to MAVS which leads to the activation of TBK1 and phosphorylation of IRF3 and phosphorylated IRF3 translocates into nucleus to promote antiviral gene transcription. Exhibits an antiproliferative activity via the up-regulation of cell cycle negative regulators CDKN1A/p21 and CDKN1B/p27. Normally, CDKN1B/p27 turnover is regulated by COPS5, which binds CDKN1B/p27 in the nucleus and exports it to the cytoplasm for ubiquitin-dependent degradation. IFIT3 sequesters COPS5 in the cytoplasm, thereby increasing nuclear CDKN1B/p27 protein levels. Upregulates CDKN1A/p21 by downregulating MYC, a repressor of CDKN1A/p21. Can negatively regulate the apoptotic effects of IFIT2.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 128-331 of mouse IFIT3 (NP_034631.1).
PurificationAffinity purification
Gene ID15959
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:1000
IHC 1:100 - 1:200
IF 1:50 - 1:200

All Names

AlternameIFIT3; CIG-49; GARG-49; IFI60; IFIT4; IRG2; ISG60; P60; RIG-G; cig41
📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Certificate of Analysis (PDF)🧪MSDS
Material safety data sheet (PDF)

Conjugated Antibody

This product is also available conjugated. Format: E45R25357N-Conjugate. Price: $485 / Size: 100μl.

E45R25357N-FITC$485 / 100μlE45R25357N-Biotin$485 / 100μlE45R25357N-HRP$485 / 100μlE45R25357N-AP$485 / 100μlE45R25357N-AF350$485 / 100μlE45R25357N-AF405M$485 / 100μlE45R25357N-AF488$485 / 100μlE45R25357N-AF514$485 / 100μlE45R25357N-AF532$485 / 100μlE45R25357N-AF555$485 / 100μlE45R25357N-AF568$485 / 100μlE45R25357N-AF405S$485 / 100μlE45R25357N-AF405L$485 / 100μlE45R25357N-AF546$485 / 100μlE45R25357N-AF594$485 / 100μlE45R25357N-AF610$485 / 100μlE45R25357N-AF635$485 / 100μlE45R25357N-AF647$485 / 100μlE45R25357N-AF680$485 / 100μlE45R25357N-AF700$485 / 100μlE45R25357N-AF750$485 / 100μlE45R25357N-AF790$485 / 100μlE45R25357N-APC$485 / 100μlE45R25357N-PE$485 / 100μlE45R25357N-Cy3$485 / 100μlE45R25357N-Cy5$485 / 100μlE45R25357N-Cy5.5$485 / 100μlE45R25357N-Cy7$485 / 100μlE45R25357N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

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IFIT3 Rabbit pAb | EnoGene Biotech Co. Ltd