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DDB1 Rabbit pAb
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5516585
TypePolyclonal Antibodies
HostRabbit
Positive controlBT-474, SW620, 293T, Mouse eye, Mouse testis, Mouse breast
IsotypeIgG
SummaryThe protein encoded by this gene is the large subunit (p127) of the heterodimeric DNA damage-binding (DDB) complex while another protein (p48) forms the small subunit. This protein complex functions in nucleotide-excision repair and binds to DNA following UV damage. Defective activity of this complex causes the repair defect in patients with xeroderma pigmentosum complementation group E (XPE) - an autosomal recessive disorder characterized by photosensitivity and early onset of carcinomas. However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. The protein encoded by this gene also functions as an adaptor molecule for the cullin 4 (CUL4) ubiquitin E3 ligase complex by facilitating the binding of substrates to this complex and the ubiquitination of proteins.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenA synthetic peptide of human DDB1
PurificationAffinity purification
Gene ID1642
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:1000
IHC 1:50 - 1:100
IF 1:50 - 1:100
IHC 1:50 - 1:100
IF 1:50 - 1:100
All Names
AlternameDDB1; DDBA; UV-DDB1; XAP1; XPCE; XPE; XPE-BF
Conjugated Antibody
This product is also available conjugated. Format: E45R25004N-Conjugate. Price: $485 / Size: 100μl.
E45R25004N-FITC$485 / 100μlE45R25004N-Biotin$485 / 100μlE45R25004N-HRP$485 / 100μlE45R25004N-AP$485 / 100μlE45R25004N-AF350$485 / 100μlE45R25004N-AF405M$485 / 100μlE45R25004N-AF488$485 / 100μlE45R25004N-AF514$485 / 100μlE45R25004N-AF532$485 / 100μlE45R25004N-AF555$485 / 100μlE45R25004N-AF568$485 / 100μlE45R25004N-AF405S$485 / 100μlE45R25004N-AF405L$485 / 100μlE45R25004N-AF546$485 / 100μlE45R25004N-AF594$485 / 100μlE45R25004N-AF610$485 / 100μlE45R25004N-AF635$485 / 100μlE45R25004N-AF647$485 / 100μlE45R25004N-AF680$485 / 100μlE45R25004N-AF700$485 / 100μlE45R25004N-AF750$485 / 100μlE45R25004N-AF790$485 / 100μlE45R25004N-APC$485 / 100μlE45R25004N-PE$485 / 100μlE45R25004N-Cy3$485 / 100μlE45R25004N-Cy5$485 / 100μlE45R25004N-Cy5.5$485 / 100μlE45R25004N-Cy7$485 / 100μlE45R25004N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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