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RPA2 Rabbit pAb
Human, Mouse, Rat
WB (Mouse liver, Mouse adipose-derived stem cells, Mus musculus, Homo sapiens, Triticum aestivum L.)
IF (Mus musculus)
IF (Mus musculus)
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5515775
TypePolyclonal Antibodies
HostRabbit
Positive control293T, 293T+UV, NIH/3T3, C6
IsotypeIgG
SummaryAs part of the heterotrimeric replication protein A complex (RPA/RP-A, binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation. Through recruitment of ATRIP activates the ATR kinase a master regulator of the DNA damage response. It is required for the recruitment of the DNA double-strand break repair factors RAD51 and RAD52 to chromatin in response to DNA damage. Also recruits to sites of DNA damage proteins like XPA and XPG that are involved in nucleotide excision repair and is required for this mechanism of DNA repair. Plays also a role in base excision repair (BER probably through interaction with UNG. Also recruits SMARCAL1/HARP, which is involved in replication fork restart, to sites of DNA damage. May also play a role in telomere maintenance.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 80-270 of human RPA2 (NP_002937.1).
PurificationAffinity purification
Gene ID6118
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:100
IP 1:50 - 1:200
IHC 1:50 - 1:200
IF 1:50 - 1:100
IP 1:50 - 1:200
All Names
AlternameREPA2; RP-A p32; RP-A p34; RPA32; RPA2; RP-Ap32; RP-Ap34
Conjugated Antibody
This product is also available conjugated. Format: E45R24706N-Conjugate. Price: $485 / Size: 100μl.
E45R24706N-FITC$485 / 100μlE45R24706N-Biotin$485 / 100μlE45R24706N-HRP$485 / 100μlE45R24706N-AP$485 / 100μlE45R24706N-AF350$485 / 100μlE45R24706N-AF405M$485 / 100μlE45R24706N-AF488$485 / 100μlE45R24706N-AF514$485 / 100μlE45R24706N-AF532$485 / 100μlE45R24706N-AF555$485 / 100μlE45R24706N-AF568$485 / 100μlE45R24706N-AF405S$485 / 100μlE45R24706N-AF405L$485 / 100μlE45R24706N-AF546$485 / 100μlE45R24706N-AF594$485 / 100μlE45R24706N-AF610$485 / 100μlE45R24706N-AF635$485 / 100μlE45R24706N-AF647$485 / 100μlE45R24706N-AF680$485 / 100μlE45R24706N-AF700$485 / 100μlE45R24706N-AF750$485 / 100μlE45R24706N-AF790$485 / 100μlE45R24706N-APC$485 / 100μlE45R24706N-PE$485 / 100μlE45R24706N-Cy3$485 / 100μlE45R24706N-Cy5$485 / 100μlE45R24706N-Cy5.5$485 / 100μlE45R24706N-Cy7$485 / 100μlE45R24706N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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