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GPX4 Rabbit pAb
Human, Mouse, Rat
WB (Mouse liver, Homo sapiens, Mus musculus, Rattus norvegicus, Gallus gallus)
IHC (Mus musculus)
IF (Rattus norvegicus)
IHC (Mus musculus)
IF (Rattus norvegicus)
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5515929
TypePolyclonal Antibodies
HostRabbit
Positive controlJurkat, Mouse testis, Rat testis
IsotypeIgG
SummaryThe protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of hydrogen peroxide, organic hydroperoxides and lipid hydroperoxides, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme has a high preference for lipid hydroperoxides and protects cells against membrane lipid peroxidation and cell death. It is also required for normal sperm development; thus, it has been identified as a 'moonlighting' protein because of its ability to serve dual functions as a peroxidase, as well as a structural protein in mature spermatozoa. Mutations in this gene are associated with Sedaghatian type of spondylometaphyseal dysplasia (SMDS). This isozyme is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 30-197 of human GPX4 (NP_002076.2).
PurificationAffinity purification
Gene ID2879
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
IP 1:50 - 1:200
IHC 1:50 - 1:200
IF 1:50 - 1:200
IP 1:50 - 1:200
All Names
AlternameGPX4; GPx-4; GSHPx-4; MCSP; PHGPx; SMDS; snGPx; snPHGPx
Conjugated Antibody
This product is also available conjugated. Format: E45R24475N-Conjugate. Price: $485 / Size: 100μl.
E45R24475N-FITC$485 / 100μlE45R24475N-Biotin$485 / 100μlE45R24475N-HRP$485 / 100μlE45R24475N-AP$485 / 100μlE45R24475N-AF350$485 / 100μlE45R24475N-AF405M$485 / 100μlE45R24475N-AF488$485 / 100μlE45R24475N-AF514$485 / 100μlE45R24475N-AF532$485 / 100μlE45R24475N-AF555$485 / 100μlE45R24475N-AF568$485 / 100μlE45R24475N-AF405S$485 / 100μlE45R24475N-AF405L$485 / 100μlE45R24475N-AF546$485 / 100μlE45R24475N-AF594$485 / 100μlE45R24475N-AF610$485 / 100μlE45R24475N-AF635$485 / 100μlE45R24475N-AF647$485 / 100μlE45R24475N-AF680$485 / 100μlE45R24475N-AF700$485 / 100μlE45R24475N-AF750$485 / 100μlE45R24475N-AF790$485 / 100μlE45R24475N-APC$485 / 100μlE45R24475N-PE$485 / 100μlE45R24475N-Cy3$485 / 100μlE45R24475N-Cy5$485 / 100μlE45R24475N-Cy5.5$485 / 100μlE45R24475N-Cy7$485 / 100μlE45R24475N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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