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LAMC2 Rabbit pAb
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5515590
TypePolyclonal Antibodies
HostRabbit
Positive controlRat lung
IsotypeIgG
SummaryThis gene encodes the gamma chain isoform laminin, gamma 2. The gamma 2 chain, formerly thought to be a truncated version of beta chain (B2t), is highly homologous to the gamma 1 chain; however, it lacks domain VI, and domains V, IV and III are shorter. It is expressed in several fetal tissues but differently from gamma 1, and is specifically localized to epithelial cells in skin, lung and kidney. The gamma 2 chain together with alpha 3 and beta 3 chains constitute laminin 5 (earlier known as kalinin), which is an integral part of the anchoring filaments that connect epithelial cells to the underlying basement membrane. The epithelium-specific expression of the gamma 2 chain implied its role as an epithelium attachment molecule, and mutations in this gene have been associated with junctional epidermolysis bullosa, a skin disease characterized by blisters due to disruption of the epidermal-dermal junction. Two transcript variants resulting from alternative splicing of the 3' terminal exon, and encoding different isoforms of gamma 2 chain, have been described. The two variants are differentially expressed in embryonic tissues, however, the biological significance of the two forms is not known. Transcript variants utilizing alternative polyA_signal have also been noted in literature.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 862-1111 of human LAMC2 (NP_061486.2).
PurificationAffinity purification
Gene ID3918
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IF 1:50 - 1:100
IF 1:50 - 1:100
All Names
AlternameLAMC2; B2T; BM600; CSF; EBR2; EBR2A; LAMB2T; LAMNB2
Conjugated Antibody
This product is also available conjugated. Format: E45R24418N-Conjugate. Price: $485 / Size: 100μl.
E45R24418N-FITC$485 / 100μlE45R24418N-Biotin$485 / 100μlE45R24418N-HRP$485 / 100μlE45R24418N-AP$485 / 100μlE45R24418N-AF350$485 / 100μlE45R24418N-AF405M$485 / 100μlE45R24418N-AF488$485 / 100μlE45R24418N-AF514$485 / 100μlE45R24418N-AF532$485 / 100μlE45R24418N-AF555$485 / 100μlE45R24418N-AF568$485 / 100μlE45R24418N-AF405S$485 / 100μlE45R24418N-AF405L$485 / 100μlE45R24418N-AF546$485 / 100μlE45R24418N-AF594$485 / 100μlE45R24418N-AF610$485 / 100μlE45R24418N-AF635$485 / 100μlE45R24418N-AF647$485 / 100μlE45R24418N-AF680$485 / 100μlE45R24418N-AF700$485 / 100μlE45R24418N-AF750$485 / 100μlE45R24418N-AF790$485 / 100μlE45R24418N-APC$485 / 100μlE45R24418N-PE$485 / 100μlE45R24418N-Cy3$485 / 100μlE45R24418N-Cy5$485 / 100μlE45R24418N-Cy5.5$485 / 100μlE45R24418N-Cy7$485 / 100μlE45R24418N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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