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Pan-Akt Rabbit pAb
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5515731
TypePolyclonal Antibodies
HostRabbit
Positive controlMCF7, Mouse brain, Rat brain
IsotypeIgG
SummaryHuman AKT serine-threonine protein kinase family includes three members AKT1,AKT2, AKT3, which are also often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT proteins all have an N-terminal pleckstrin homology domain, a serine/threonine-specific kinase domain and a C-terminal regulatory domain. These proteins are phosphorylated by phosphoinositide 3-kinase (PI3K). AKT/PI3K forms a key component of many signalling pathways that involve the binding of membrane-bound ligands such as receptor tyrosine kinases, G-protein coupled receptors, and integrin-linked kinase. These AKT proteins therefore regulate a wide variety of cellular functions including cell proliferation, survival, metabolism, and angiogenesis in both normal and malignant cells. AKT proteins are recruited to the cell membrane by phosphatidylinositol 3,4,5-trisphosphate (PIP3) after phosphorylation of phosphatidylinositol 4,5-bisphosphate (PIP2) by PI3K. Subsequent phosphorylation of both threonine residue 308 and serine residue 473 is required for full activation of the AKT1 protein encoded by this gene.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenA synthetic peptide of human AKT1/AKT2/AKT3
PurificationAffinity purification
Gene ID207/208/10000
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:1000
IHC 1:50 - 1:100
IF 1:50 - 1:100
IP 1:50 - 1:100
IHC 1:50 - 1:100
IF 1:50 - 1:100
IP 1:50 - 1:100
All Names
AlternameAKT1/AKT2/AKT3
Conjugated Antibody
This product is also available conjugated. Format: E45R24230N-Conjugate. Price: $485 / Size: 100μl.
E45R24230N-FITC$485 / 100μlE45R24230N-Biotin$485 / 100μlE45R24230N-HRP$485 / 100μlE45R24230N-AP$485 / 100μlE45R24230N-AF350$485 / 100μlE45R24230N-AF405M$485 / 100μlE45R24230N-AF488$485 / 100μlE45R24230N-AF514$485 / 100μlE45R24230N-AF532$485 / 100μlE45R24230N-AF555$485 / 100μlE45R24230N-AF568$485 / 100μlE45R24230N-AF405S$485 / 100μlE45R24230N-AF405L$485 / 100μlE45R24230N-AF546$485 / 100μlE45R24230N-AF594$485 / 100μlE45R24230N-AF610$485 / 100μlE45R24230N-AF635$485 / 100μlE45R24230N-AF647$485 / 100μlE45R24230N-AF680$485 / 100μlE45R24230N-AF700$485 / 100μlE45R24230N-AF750$485 / 100μlE45R24230N-AF790$485 / 100μlE45R24230N-APC$485 / 100μlE45R24230N-PE$485 / 100μlE45R24230N-Cy3$485 / 100μlE45R24230N-Cy5$485 / 100μlE45R24230N-Cy5.5$485 / 100μlE45R24230N-Cy7$485 / 100μlE45R24230N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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