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[KO Validated] Sonic Hedgehog Rabbit pAb

E45R24161NDatasheetCOAMSDS
Human
Q15465
$477/ 100 µl
Quantity
Total: $477

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5505939
TypePolyclonal Antibodies
HostRabbit
Positive controlHeLa
IsotypeIgG
SummaryThis gene encodes a protein that is instrumental in patterning the early embryo. It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. Of three human proteins showing sequence and functional similarity to the sonic hedgehog protein of Drosophila, this protein is the most similar. The protein is made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the developing embryo. Defects in this protein or in its signalling pathway are a cause of holoprosencephaly (HPE). It is also thought that mutations in this gene or in its signalling pathway may be responsible for VACTERL syndrome. Additionally, mutations in a long range enhancer located approximately 1 megabase upstream of this gene disrupt limb patterning and can result in preaxial polydactyly.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price477$
ImmunogenA synthetic peptide of human Sonic Hedgehog (Sonic Hedgehog (Shh))
PurificationAffinity purification
Gene ID6469
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200

All Names

AlternameSHH; HHG1; HLP3; HPE3; MCOPCB5; SMMCI; TPT; TPTPS
📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Certificate of Analysis (PDF)🧪MSDS
Material safety data sheet (PDF)

Conjugated Antibody

This product is also available conjugated. Format: E45R24161N-Conjugate. Price: $485 / Size: 100μl.

E45R24161N-FITC$485 / 100μlE45R24161N-Biotin$485 / 100μlE45R24161N-HRP$485 / 100μlE45R24161N-AP$485 / 100μlE45R24161N-AF350$485 / 100μlE45R24161N-AF405M$485 / 100μlE45R24161N-AF488$485 / 100μlE45R24161N-AF514$485 / 100μlE45R24161N-AF532$485 / 100μlE45R24161N-AF555$485 / 100μlE45R24161N-AF568$485 / 100μlE45R24161N-AF405S$485 / 100μlE45R24161N-AF405L$485 / 100μlE45R24161N-AF546$485 / 100μlE45R24161N-AF594$485 / 100μlE45R24161N-AF610$485 / 100μlE45R24161N-AF635$485 / 100μlE45R24161N-AF647$485 / 100μlE45R24161N-AF680$485 / 100μlE45R24161N-AF700$485 / 100μlE45R24161N-AF750$485 / 100μlE45R24161N-AF790$485 / 100μlE45R24161N-APC$485 / 100μlE45R24161N-PE$485 / 100μlE45R24161N-Cy3$485 / 100μlE45R24161N-Cy5$485 / 100μlE45R24161N-Cy5.5$485 / 100μlE45R24161N-Cy7$485 / 100μlE45R24161N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

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[KO Validated] Sonic Hedgehog Rabbit pAb | EnoGene Biotech Co. Ltd