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TMED2 Rabbit pAb
Human, Mouse, Rat
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5506184
TypePolyclonal Antibodies
HostRabbit
Positive controlU-87MG, HepG2, Mouse liver, Mouse kidney, Rat spleen, Rat lung, Rat liver
IsotypeIgG
SummaryInvolved in vesicular protein trafficking. Mainly functions in the early secretory pathway but also in post-Golgi membranes. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED10 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft-like microdomains of the ER. Recognizes GPI anchors structural remodeled in the ER by PGAP1 and MPPE1. In COPI vesicle-mediated retrograde transport inhibits the GTPase-activating activity of ARFGAP1 towards ARF1 thus preventing immature uncoating and allowing cargo selection to take place. Involved in trafficking of G protein-coupled receptors (GPCRs. Regulates F2RL1, OPRM1 and P2RY4 exocytic trafficking from the Golgi to the plasma membrane thus contributing to receptor resensitization. Facilitates CASR maturation and stabilization in the early secretory pathway and increases CASR plasma membrane targeting. Proposed to be involved in organization of intracellular membranes such as the maintenance of the Golgi apparatus. May also play a role in the biosynthesis of secreted cargo such as eventual processing.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 60-170 of human TMED2 (NP_006806.1).
PurificationAffinity purification
Gene ID10959
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IF 1:50 - 1:200
IF 1:50 - 1:200
All Names
AlternameP24A; RNP24; p24; p24b1; p24beta1; TMED2
Conjugated Antibody
This product is also available conjugated. Format: E45R23845N-Conjugate. Price: $485 / Size: 100μl.
E45R23845N-FITC$485 / 100μlE45R23845N-Biotin$485 / 100μlE45R23845N-HRP$485 / 100μlE45R23845N-AP$485 / 100μlE45R23845N-AF350$485 / 100μlE45R23845N-AF405M$485 / 100μlE45R23845N-AF488$485 / 100μlE45R23845N-AF514$485 / 100μlE45R23845N-AF532$485 / 100μlE45R23845N-AF555$485 / 100μlE45R23845N-AF568$485 / 100μlE45R23845N-AF405S$485 / 100μlE45R23845N-AF405L$485 / 100μlE45R23845N-AF546$485 / 100μlE45R23845N-AF594$485 / 100μlE45R23845N-AF610$485 / 100μlE45R23845N-AF635$485 / 100μlE45R23845N-AF647$485 / 100μlE45R23845N-AF680$485 / 100μlE45R23845N-AF700$485 / 100μlE45R23845N-AF750$485 / 100μlE45R23845N-AF790$485 / 100μlE45R23845N-APC$485 / 100μlE45R23845N-PE$485 / 100μlE45R23845N-Cy3$485 / 100μlE45R23845N-Cy5$485 / 100μlE45R23845N-Cy5.5$485 / 100μlE45R23845N-Cy7$485 / 100μlE45R23845N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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