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RBM7 Rabbit pAb
Human, Mouse
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5506160
TypePolyclonal Antibodies
HostRabbit
Positive controlA-549, Jurkat, Mouse thymus
IsotypeIgG
SummaryRNA-binding subunit of the trimeric nuclear exosome targeting (NEXT complex, a complex that functions as an RNA exosome cofactor that directs a subset of non-coding short-lived RNAs for exosomal degradation. NEXT is involved in surveillance and turnover of aberrant transcripts and non-coding RNAs. Binds preferentially polyuridine sequences and associates with newly synthesized RNAs, including pre-mRNAs and short-lived exosome substrates such as promoter upstream transcripts (PROMPTs, enhancer RNAs (eRNAs, and 3'-extended products from small nuclear RNAs (snRNAs. Participates in several biological processes including DNA damage response (DDR and stress response. During stress response, activation of the p38MAPK-MK2 pathway decreases RBM7-RNA-binding and subsequently the RNA exosome degradation activities, thereby modulating the turnover of non-coding transcriptome. Participates in DNA damage response (DDR, through its interaction with MEPCE and LARP7, the core subunits of 7SK snRNP complex, that release the positive transcription elongation factor b (P-TEFb complex from the 7SK snRNP. In turn, activation of P-TEFb complex induces the transcription of P-TEFb-dependent DDR genes to promote cell viability.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-266 of human RBM7 (NP_057174.1).
PurificationAffinity purification
Gene ID10179
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
All Names
AlternameRBM7
Conjugated Antibody
This product is also available conjugated. Format: E45R23830N-Conjugate. Price: $485 / Size: 100μl.
E45R23830N-FITC$485 / 100μlE45R23830N-Biotin$485 / 100μlE45R23830N-HRP$485 / 100μlE45R23830N-AP$485 / 100μlE45R23830N-AF350$485 / 100μlE45R23830N-AF405M$485 / 100μlE45R23830N-AF488$485 / 100μlE45R23830N-AF514$485 / 100μlE45R23830N-AF532$485 / 100μlE45R23830N-AF555$485 / 100μlE45R23830N-AF568$485 / 100μlE45R23830N-AF405S$485 / 100μlE45R23830N-AF405L$485 / 100μlE45R23830N-AF546$485 / 100μlE45R23830N-AF594$485 / 100μlE45R23830N-AF610$485 / 100μlE45R23830N-AF635$485 / 100μlE45R23830N-AF647$485 / 100μlE45R23830N-AF680$485 / 100μlE45R23830N-AF700$485 / 100μlE45R23830N-AF750$485 / 100μlE45R23830N-AF790$485 / 100μlE45R23830N-APC$485 / 100μlE45R23830N-PE$485 / 100μlE45R23830N-Cy3$485 / 100μlE45R23830N-Cy5$485 / 100μlE45R23830N-Cy5.5$485 / 100μlE45R23830N-Cy7$485 / 100μlE45R23830N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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