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SRPK2 Rabbit pAb
Human, Mouse, Rat
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5506164
TypePolyclonal Antibodies
HostRabbit
Positive controlMouse heart, Mouse brain, Rat brain
IsotypeIgG
SummarySerine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1 expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1 expression. Phosphorylates ACIN1, and redistributes it from the nuclear speckles to the nucleoplasm, resulting in cyclin A1 but not cyclin A2 up-regulation. Plays an essential role in spliceosomal B complex formation via the phosphorylation of DDX23/PRP28. Probably by phosphorylating DDX23, leads to the suppression of incorrect R-loops formed during transcription; R-loops are composed of a DNA:RNA hybrid and the associated non-template single-stranded DNA. Can mediate hepatitis B virus (HBV core protein phosphorylation. Plays a negative role in the regulation of HBV replication through a mechanism not involving the phosphorylation of the core protein but by reducing the packaging efficiency of the pregenomic RNA (pgRNA without affecting the formation of the viral core particles.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 420-520 of human SRPK2 (NP_872633.1).
PurificationAffinity purification
Gene ID6733
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IF 1:50 - 1:200
IF 1:50 - 1:200
All Names
AlternameSFRSK2; SRPK2
Conjugated Antibody
This product is also available conjugated. Format: E45R23784N-Conjugate. Price: $485 / Size: 100μl.
E45R23784N-FITC$485 / 100μlE45R23784N-Biotin$485 / 100μlE45R23784N-HRP$485 / 100μlE45R23784N-AP$485 / 100μlE45R23784N-AF350$485 / 100μlE45R23784N-AF405M$485 / 100μlE45R23784N-AF488$485 / 100μlE45R23784N-AF514$485 / 100μlE45R23784N-AF532$485 / 100μlE45R23784N-AF555$485 / 100μlE45R23784N-AF568$485 / 100μlE45R23784N-AF405S$485 / 100μlE45R23784N-AF405L$485 / 100μlE45R23784N-AF546$485 / 100μlE45R23784N-AF594$485 / 100μlE45R23784N-AF610$485 / 100μlE45R23784N-AF635$485 / 100μlE45R23784N-AF647$485 / 100μlE45R23784N-AF680$485 / 100μlE45R23784N-AF700$485 / 100μlE45R23784N-AF750$485 / 100μlE45R23784N-AF790$485 / 100μlE45R23784N-APC$485 / 100μlE45R23784N-PE$485 / 100μlE45R23784N-Cy3$485 / 100μlE45R23784N-Cy5$485 / 100μlE45R23784N-Cy5.5$485 / 100μlE45R23784N-Cy7$485 / 100μlE45R23784N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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