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NUAK1 Rabbit pAb
Human, Rat
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5506269
TypePolyclonal Antibodies
HostRabbit
Positive controlrat heart
IsotypeIgG
SummarySerine/threonine-protein kinase involved in various processes such as cell adhesion, regulation of cell ploidy and senescence, cell proliferation and tumor progression. Phosphorylates ATM, CASP6, LATS1, PPP1R12A and p53/TP53. Acts as a regulator of cellular senescence and cellular ploidy by mediating phosphorylation of 'Ser-464' of LATS1, thereby controlling its stability. Controls cell adhesion by regulating activity of the myosin protein phosphatase 1 (PP1 complex. Acts by mediating phosphorylation of PPP1R12A subunit of myosin PP1: phosphorylated PPP1R12A then interacts with 14-3-3, leading to reduced dephosphorylation of myosin MLC2 by myosin PP1. May be involved in DNA damage response: phosphorylates p53/TP53 at 'Ser-15' and 'Ser-392' and is recruited to the CDKN1A/WAF1 promoter to participate in transcription activation by p53/TP53. May also act as a tumor malignancy-associated factor by promoting tumor invasion and metastasis under regulation and phosphorylation by AKT1. Suppresses Fas-induced apoptosis by mediating phosphorylation of CASP6, thereby suppressing the activation of the caspase and the subsequent cleavage of CFLAR. Regulates UV radiation-induced DNA damage response mediated by CDKN1A. In association with STK11, phosphorylates CDKN1A in response to UV radiation and contributes to its degradation which is necessary for optimal DNA repair.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 362-661 of human NUAK1 (NP_055655.1).
PurificationAffinity purification
Gene ID9891
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:200 - 1:2000
All Names
AlternameNUAK1; ARK5
Conjugated Antibody
This product is also available conjugated. Format: E45R23644N-Conjugate. Price: $485 / Size: 100μl.
E45R23644N-FITC$485 / 100μlE45R23644N-Biotin$485 / 100μlE45R23644N-HRP$485 / 100μlE45R23644N-AP$485 / 100μlE45R23644N-AF350$485 / 100μlE45R23644N-AF405M$485 / 100μlE45R23644N-AF488$485 / 100μlE45R23644N-AF514$485 / 100μlE45R23644N-AF532$485 / 100μlE45R23644N-AF555$485 / 100μlE45R23644N-AF568$485 / 100μlE45R23644N-AF405S$485 / 100μlE45R23644N-AF405L$485 / 100μlE45R23644N-AF546$485 / 100μlE45R23644N-AF594$485 / 100μlE45R23644N-AF610$485 / 100μlE45R23644N-AF635$485 / 100μlE45R23644N-AF647$485 / 100μlE45R23644N-AF680$485 / 100μlE45R23644N-AF700$485 / 100μlE45R23644N-AF750$485 / 100μlE45R23644N-AF790$485 / 100μlE45R23644N-APC$485 / 100μlE45R23644N-PE$485 / 100μlE45R23644N-Cy3$485 / 100μlE45R23644N-Cy5$485 / 100μlE45R23644N-Cy5.5$485 / 100μlE45R23644N-Cy7$485 / 100μlE45R23644N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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