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XBP1 Rabbit pAb

E45R23622NDatasheetCOAMSDS
Human, Mouse, Rat
WB (RAW264.7, Mus musculus, Homo sapiens, Rattus norvegicus)
IF (Rattus norvegicus)
IHC (Rattus norvegicus)
P17861
$409/ 100 µl
Quantity
Total: $409

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5505760
TypePolyclonal Antibodies
HostRabbit
Positive controlHT-29, 293T, Rat lung
IsotypeIgG
SummaryThis gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1). The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor. The isoform encoded by the unspliced mRNA, XBP1(U), is constitutively expressed, and thought to function as a negative feedback regulator of XBP1(S), which shuts off transcription of target genes during the recovery phase of ER stress. A pseudogene of XBP1 has been identified and localized to chromosome 5.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-261 of human XBP1 (NP_005071.2).
PurificationAffinity purification
Gene ID7494
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IF 1:50 - 1:200

All Names

AlternameXBP1; TREB-5; TREB5; XBP-1; XBP2; XBP1s; CBX1
📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Certificate of Analysis (PDF)🧪MSDS
Material safety data sheet (PDF)

Conjugated Antibody

This product is also available conjugated. Format: E45R23622N-Conjugate. Price: $485 / Size: 100μl.

E45R23622N-FITC$485 / 100μlE45R23622N-Biotin$485 / 100μlE45R23622N-HRP$485 / 100μlE45R23622N-AP$485 / 100μlE45R23622N-AF350$485 / 100μlE45R23622N-AF405M$485 / 100μlE45R23622N-AF488$485 / 100μlE45R23622N-AF514$485 / 100μlE45R23622N-AF532$485 / 100μlE45R23622N-AF555$485 / 100μlE45R23622N-AF568$485 / 100μlE45R23622N-AF405S$485 / 100μlE45R23622N-AF405L$485 / 100μlE45R23622N-AF546$485 / 100μlE45R23622N-AF594$485 / 100μlE45R23622N-AF610$485 / 100μlE45R23622N-AF635$485 / 100μlE45R23622N-AF647$485 / 100μlE45R23622N-AF680$485 / 100μlE45R23622N-AF700$485 / 100μlE45R23622N-AF750$485 / 100μlE45R23622N-AF790$485 / 100μlE45R23622N-APC$485 / 100μlE45R23622N-PE$485 / 100μlE45R23622N-Cy3$485 / 100μlE45R23622N-Cy5$485 / 100μlE45R23622N-Cy5.5$485 / 100μlE45R23622N-Cy7$485 / 100μlE45R23622N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

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XBP1 Rabbit pAb | EnoGene Biotech Co. Ltd