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ZCCHC3 Rabbit pAb

Human, Mouse
Q9NUD5
$409/ 100 µl
Quantity
Total: $409

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5506340
TypePolyclonal Antibodies
HostRabbit
Positive controlLO2, mouse liver
IsotypeIgG
SummaryNucleic acid-binding protein involved in innate immune response to DNA and RNA viruses. Binds DNA and RNA in the cytoplasm and acts by promoting recognition of viral nucleic acids by virus sensors, such as DDX58/RIG-I, IFIH1/MDA5 and CGAS. Acts as a co-sensor for recognition of double-stranded DNA (dsDNA by cGAS in the cytoplasm, thereby playing a role in innate immune response to cytosolic dsDNA and DNA virus. Binds dsDNA and probably acts by promoting sensing of dsDNA by CGAS, leading to enhance CGAS oligomerization and activation. Promotes sensing of viral RNA by RIG-I-like receptors proteins DDX58/RIG-I and IFIH1/MDA5 via two mechanisms: binds double-stranded RNA (dsRNA, enhancing the binding of DDX58/RIG-I and IFIH1/MDA5 to dsRNA and promotes 'Lys-63'-linked ubiquitination and subsequent activation of DDX58/RIG-I and IFIH1/MDA5.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 215-335 of human ZCCHC3 (NP_149080.2).
PurificationAffinity purification
Gene ID85364
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IF 1:50 - 1:200

All Names

AlternameZCCHC3; C20orf99

Conjugated Antibody

This product is also available conjugated. Format: E45R23584N-Conjugate. Price: $485 / Size: 100μl.

E45R23584N-FITC$485 / 100μlE45R23584N-Biotin$485 / 100μlE45R23584N-HRP$485 / 100μlE45R23584N-AP$485 / 100μlE45R23584N-AF350$485 / 100μlE45R23584N-AF405M$485 / 100μlE45R23584N-AF488$485 / 100μlE45R23584N-AF514$485 / 100μlE45R23584N-AF532$485 / 100μlE45R23584N-AF555$485 / 100μlE45R23584N-AF568$485 / 100μlE45R23584N-AF405S$485 / 100μlE45R23584N-AF405L$485 / 100μlE45R23584N-AF546$485 / 100μlE45R23584N-AF594$485 / 100μlE45R23584N-AF610$485 / 100μlE45R23584N-AF635$485 / 100μlE45R23584N-AF647$485 / 100μlE45R23584N-AF680$485 / 100μlE45R23584N-AF700$485 / 100μlE45R23584N-AF750$485 / 100μlE45R23584N-AF790$485 / 100μlE45R23584N-APC$485 / 100μlE45R23584N-PE$485 / 100μlE45R23584N-Cy3$485 / 100μlE45R23584N-Cy5$485 / 100μlE45R23584N-Cy5.5$485 / 100μlE45R23584N-Cy7$485 / 100μlE45R23584N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

ZCCHC3 Rabbit pAb | EnoGene Biotech Co. Ltd