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ATOH8 Rabbit pAb
Mouse, Rat
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5506341
TypePolyclonal Antibodies
HostRabbit
Positive controlMouse brain, Mouse kidney
IsotypeIgG
SummaryTranscription factor that binds a palindromic (canonical core consensus DNA sequence 5'-CANNTG- 3' known as an E-box element, possibly as a heterodimer with other bHLH proteins. Regulates endothelial cell proliferation, migration and tube-like structures formation. Modulates endothelial cell differentiation through NOS3. May be implicated in specification and differentiation of neuronal cell lineages in the brain (By similarity. May participate in kidney development and may be involved in podocyte differentiation (By similarity. During early embryonic development is involved in tissue-specific differentiation processes that are dependent on class II bHLH factors and namely modulates the differentiation program initiated by the pro-endocrine factor NEUROG3 (By similarity. During myogenesis, may play a role during the transition of myoblasts from the proliferative phase to the differentiation phase (By similarity. Positively regulates HAMP transcription in two ways, firstly by acting directly on the HAMP promoter via E-boxes binding and indirectly through increased phosphorylation of SMAD protein complex. Repress NEUROG3-dependent gene activation in a gene-specific manner through at least two mechanisms; requires only either the sequestering of a general partner such as TCF3 through heterodimerization, either also requires binding of the bHLH domain to DNA via a basic motif (By similarity.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenA synthetic peptide of human ATOH8.
PurificationAffinity purification
Gene ID84913
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
All Names
AlternameATOH8; HATH6; bHLHa21
Conjugated Antibody
This product is also available conjugated. Format: E45R23583N-Conjugate. Price: $485 / Size: 100μl.
E45R23583N-FITC$485 / 100μlE45R23583N-Biotin$485 / 100μlE45R23583N-HRP$485 / 100μlE45R23583N-AP$485 / 100μlE45R23583N-AF350$485 / 100μlE45R23583N-AF405M$485 / 100μlE45R23583N-AF488$485 / 100μlE45R23583N-AF514$485 / 100μlE45R23583N-AF532$485 / 100μlE45R23583N-AF555$485 / 100μlE45R23583N-AF568$485 / 100μlE45R23583N-AF405S$485 / 100μlE45R23583N-AF405L$485 / 100μlE45R23583N-AF546$485 / 100μlE45R23583N-AF594$485 / 100μlE45R23583N-AF610$485 / 100μlE45R23583N-AF635$485 / 100μlE45R23583N-AF647$485 / 100μlE45R23583N-AF680$485 / 100μlE45R23583N-AF700$485 / 100μlE45R23583N-AF750$485 / 100μlE45R23583N-AF790$485 / 100μlE45R23583N-APC$485 / 100μlE45R23583N-PE$485 / 100μlE45R23583N-Cy3$485 / 100μlE45R23583N-Cy5$485 / 100μlE45R23583N-Cy5.5$485 / 100μlE45R23583N-Cy7$485 / 100μlE45R23583N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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