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TNFSF11 Rabbit pAb

Human, Mouse
O14788
$409/ 100 µl
Quantity
Total: $409

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5506390
TypePolyclonal Antibodies
HostRabbit
IsotypeIgG
SummaryThis gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced transcript variants have been found.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant protein of human TNFSF11.
PurificationAffinity purification
Gene ID8600
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200

All Names

AlternameTNFSF11; CD254; ODF; OPGL; OPTB2; RANKL; TNLG6B; TRANCE; hRANKL2; sOdf

Conjugated Antibody

This product is also available conjugated. Format: E45R23484N-Conjugate. Price: $485 / Size: 100μl.

E45R23484N-FITC$485 / 100μlE45R23484N-Biotin$485 / 100μlE45R23484N-HRP$485 / 100μlE45R23484N-AP$485 / 100μlE45R23484N-AF350$485 / 100μlE45R23484N-AF405M$485 / 100μlE45R23484N-AF488$485 / 100μlE45R23484N-AF514$485 / 100μlE45R23484N-AF532$485 / 100μlE45R23484N-AF555$485 / 100μlE45R23484N-AF568$485 / 100μlE45R23484N-AF405S$485 / 100μlE45R23484N-AF405L$485 / 100μlE45R23484N-AF546$485 / 100μlE45R23484N-AF594$485 / 100μlE45R23484N-AF610$485 / 100μlE45R23484N-AF635$485 / 100μlE45R23484N-AF647$485 / 100μlE45R23484N-AF680$485 / 100μlE45R23484N-AF700$485 / 100μlE45R23484N-AF750$485 / 100μlE45R23484N-AF790$485 / 100μlE45R23484N-APC$485 / 100μlE45R23484N-PE$485 / 100μlE45R23484N-Cy3$485 / 100μlE45R23484N-Cy5$485 / 100μlE45R23484N-Cy5.5$485 / 100μlE45R23484N-Cy7$485 / 100μlE45R23484N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

TNFSF11 Rabbit pAb | EnoGene Biotech Co. Ltd