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TRAF6 Rabbit pAb
Human, Mouse, Rat
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5506480
TypePolyclonal Antibodies
HostRabbit
Positive controlHeLa, 293T, K-562, RAW264.7, Mouse liver, Mouse brain, Rat kidney
IsotypeIgG
SummaryThe protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from, members of the TNF receptor superfamily. This protein mediates signaling from members of the TNF receptor superfamily as well as the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. This protein also interacts with the transforming growth factor (TGF) beta receptor complex and is required for Smad-independent activation of the JNK and p38 kinases. This protein has an amino terminal RING domain which is followed by four zinc-finger motifs, a central coiled-coil region and a highly conserved carboxyl terminal domain, known as the TRAF-C domain. Two alternatively spliced transcript variants, encoding an identical protein, have been reported.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenA synthetic peptide of human TRAF6.
PurificationAffinity purification
Gene ID7189
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
IHC 1:50 - 1:200
IF 1:50 - 1:200
All Names
AlternameTRAF6; MGC:3310; RNF85
Conjugated Antibody
This product is also available conjugated. Format: E45R23465N-Conjugate. Price: $485 / Size: 100μl.
E45R23465N-FITC$485 / 100μlE45R23465N-Biotin$485 / 100μlE45R23465N-HRP$485 / 100μlE45R23465N-AP$485 / 100μlE45R23465N-AF350$485 / 100μlE45R23465N-AF405M$485 / 100μlE45R23465N-AF488$485 / 100μlE45R23465N-AF514$485 / 100μlE45R23465N-AF532$485 / 100μlE45R23465N-AF555$485 / 100μlE45R23465N-AF568$485 / 100μlE45R23465N-AF405S$485 / 100μlE45R23465N-AF405L$485 / 100μlE45R23465N-AF546$485 / 100μlE45R23465N-AF594$485 / 100μlE45R23465N-AF610$485 / 100μlE45R23465N-AF635$485 / 100μlE45R23465N-AF647$485 / 100μlE45R23465N-AF680$485 / 100μlE45R23465N-AF700$485 / 100μlE45R23465N-AF750$485 / 100μlE45R23465N-AF790$485 / 100μlE45R23465N-APC$485 / 100μlE45R23465N-PE$485 / 100μlE45R23465N-Cy3$485 / 100μlE45R23465N-Cy5$485 / 100μlE45R23465N-Cy5.5$485 / 100μlE45R23465N-Cy7$485 / 100μlE45R23465N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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