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TTN Rabbit pAb
Mouse, Rat
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5506534
TypePolyclonal Antibodies
HostRabbit
IsotypeIgG
SummaryThis gene encodes a large abundant protein of striated muscle. The product of this gene is divided into two regions, a N-terminal I-band and a C-terminal A-band. The I-band, which is the elastic part of the molecule, contains two regions of tandem immunoglobulin domains on either side of a PEVK region that is rich in proline, glutamate, valine and lysine. The A-band, which is thought to act as a protein-ruler, contains a mixture of immunoglobulin and fibronectin repeats, and possesses kinase activity. An N-terminal Z-disc region and a C-terminal M-line region bind to the Z-line and M-line of the sarcomere, respectively, so that a single titin molecule spans half the length of a sarcomere. Titin also contains binding sites for muscle associated proteins so it serves as an adhesion template for the assembly of contractile machinery in muscle cells. It has also been identified as a structural protein for chromosomes. Alternative splicing of this gene results in multiple transcript variants. Considerable variability exists in the I-band, the M-line and the Z-disc regions of titin. Variability in the I-band region contributes to the differences in elasticity of different titin isoforms and, therefore, to the differences in elasticity of different muscle types. Mutations in this gene are associated with familial hypertrophic cardiomyopathy 9, and autoantibodies to titin are produced in patients with the autoimmune disease scleroderma.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant Protein of human TTN.
PurificationAffinity purification
Gene ID7273
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionIF 1:50 - 1:200
All Names
AlternameTTN; CMD1G; CMH9; CMPD4; EOMFC; HMERF; LGMD2J; MYLK5; TMD; SALMY; titin
Conjugated Antibody
This product is also available conjugated. Format: E45R23319N-Conjugate. Price: $485 / Size: 100μl.
E45R23319N-FITC$485 / 100μlE45R23319N-Biotin$485 / 100μlE45R23319N-HRP$485 / 100μlE45R23319N-AP$485 / 100μlE45R23319N-AF350$485 / 100μlE45R23319N-AF405M$485 / 100μlE45R23319N-AF488$485 / 100μlE45R23319N-AF514$485 / 100μlE45R23319N-AF532$485 / 100μlE45R23319N-AF555$485 / 100μlE45R23319N-AF568$485 / 100μlE45R23319N-AF405S$485 / 100μlE45R23319N-AF405L$485 / 100μlE45R23319N-AF546$485 / 100μlE45R23319N-AF594$485 / 100μlE45R23319N-AF610$485 / 100μlE45R23319N-AF635$485 / 100μlE45R23319N-AF647$485 / 100μlE45R23319N-AF680$485 / 100μlE45R23319N-AF700$485 / 100μlE45R23319N-AF750$485 / 100μlE45R23319N-AF790$485 / 100μlE45R23319N-APC$485 / 100μlE45R23319N-PE$485 / 100μlE45R23319N-Cy3$485 / 100μlE45R23319N-Cy5$485 / 100μlE45R23319N-Cy5.5$485 / 100μlE45R23319N-Cy7$485 / 100μlE45R23319N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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