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[KO Validated] Insulin-degrading enzyme (IDE) Rabbit pAb

E45R22885NDatasheetCOAMSDS
Human, Mouse
WB (Mus musculus)
P14735
$477/ 100 µl
Quantity
Total: $477

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5516558
TypePolyclonal Antibodies
HostRabbit
Positive controlDU145, Mouse liver
IsotypeIgG
SummaryThis gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price477$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human Insulin-degrading enzyme (Insulin-degrading enzyme (IDE)) (NP_004960.2).
PurificationAffinity purification
Gene ID3416
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IF 1:10 - 1:100

All Names

AlternameIDE; INSULYSIN
📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Certificate of Analysis (PDF)🧪MSDS
Material safety data sheet (PDF)

Conjugated Antibody

This product is also available conjugated. Format: E45R22885N-Conjugate. Price: $485 / Size: 100μl.

E45R22885N-FITC$485 / 100μlE45R22885N-Biotin$485 / 100μlE45R22885N-HRP$485 / 100μlE45R22885N-AP$485 / 100μlE45R22885N-AF350$485 / 100μlE45R22885N-AF405M$485 / 100μlE45R22885N-AF488$485 / 100μlE45R22885N-AF514$485 / 100μlE45R22885N-AF532$485 / 100μlE45R22885N-AF555$485 / 100μlE45R22885N-AF568$485 / 100μlE45R22885N-AF405S$485 / 100μlE45R22885N-AF405L$485 / 100μlE45R22885N-AF546$485 / 100μlE45R22885N-AF594$485 / 100μlE45R22885N-AF610$485 / 100μlE45R22885N-AF635$485 / 100μlE45R22885N-AF647$485 / 100μlE45R22885N-AF680$485 / 100μlE45R22885N-AF700$485 / 100μlE45R22885N-AF750$485 / 100μlE45R22885N-AF790$485 / 100μlE45R22885N-APC$485 / 100μlE45R22885N-PE$485 / 100μlE45R22885N-Cy3$485 / 100μlE45R22885N-Cy5$485 / 100μlE45R22885N-Cy5.5$485 / 100μlE45R22885N-Cy7$485 / 100μlE45R22885N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

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[KO Validated] Insulin-degrading enzyme (IDE) Rabbit pAb | EnoGene Biotech Co. Ltd