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SGOL1 Rabbit pAb
Human, Mouse, Rat
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5516173
TypePolyclonal Antibodies
HostRabbit
Positive controlA-549, HT-29, Mouse testis, Rat testis
IsotypeIgG
SummaryThe protein encoded by this gene is a member of the shugoshin family of proteins. This protein is thought to protect centromeric cohesin from cleavage during mitotic prophase by preventing phosphorylation of a cohesin subunit. Reduced expression of this gene leads to the premature loss of centromeric cohesion, mis-segregation of sister chromatids, and mitotic arrest. Evidence suggests that this protein also protects a small subset of cohesin found along the length of the chromosome arms during mitotic prophase. An isoform lacking exon 6 has been shown to play a role in the cohesion of centrioles (PMID: 16582621 and PMID:18331714). Mutations in this gene have been associated with Chronic Atrial and Intestinal Dysrhythmia (CAID) syndrome, characterized by the co-occurrence of Sick Sinus Syndrome (SSS) and Chronic Intestinal Pseudo-obstruction (CIPO) within the first four decades of life (PMID:25282101). Fibroblast cells from CAID patients exhibited both increased cell proliferation and higher rates of senescence. Pseudogenes of this gene have been found on chromosomes 1 and 7. Alternative splicing results in multiple transcript variants.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 10-100 of human SGOL1 (NP_612493.1).
PurificationAffinity purification
Gene ID151648
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IF 1:50 - 1:200
IF 1:50 - 1:200
All Names
AlternameSGO1; CAID; NY-BR-85; SGO; SGOL1
Conjugated Antibody
This product is also available conjugated. Format: E45R22765N-Conjugate. Price: $485 / Size: 100μl.
E45R22765N-FITC$485 / 100μlE45R22765N-Biotin$485 / 100μlE45R22765N-HRP$485 / 100μlE45R22765N-AP$485 / 100μlE45R22765N-AF350$485 / 100μlE45R22765N-AF405M$485 / 100μlE45R22765N-AF488$485 / 100μlE45R22765N-AF514$485 / 100μlE45R22765N-AF532$485 / 100μlE45R22765N-AF555$485 / 100μlE45R22765N-AF568$485 / 100μlE45R22765N-AF405S$485 / 100μlE45R22765N-AF405L$485 / 100μlE45R22765N-AF546$485 / 100μlE45R22765N-AF594$485 / 100μlE45R22765N-AF610$485 / 100μlE45R22765N-AF635$485 / 100μlE45R22765N-AF647$485 / 100μlE45R22765N-AF680$485 / 100μlE45R22765N-AF700$485 / 100μlE45R22765N-AF750$485 / 100μlE45R22765N-AF790$485 / 100μlE45R22765N-APC$485 / 100μlE45R22765N-PE$485 / 100μlE45R22765N-Cy3$485 / 100μlE45R22765N-Cy5$485 / 100μlE45R22765N-Cy5.5$485 / 100μlE45R22765N-Cy7$485 / 100μlE45R22765N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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