Product Information
Cite ID#EN5516162
TypePolyclonal Antibodies
HostRabbit
Positive controlU-87MG, LO2
IsotypeIgG
SummaryIn T-helper 2 (Th2 cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter; this leads to enhancement of histone H4 'Arg-3'-methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression (By similarity. Down-regulates formation of poly-SUMO chains by UBE2I/UBC9 (By similarity.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.