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KLHDC2 Rabbit pAb

E45R21698NDatasheetCOAMSDS
Rat
Q9Y2U9
$409/ 100 µl
Quantity
Total: $409

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5509341
TypePolyclonal Antibodies
HostRabbit
Positive controlrat pancreas
IsotypeIgG
SummarySubstrate-recognition component of a Cul2-RING (CRL2 E3 ubiquitin-protein ligase complex of the DesCEND (destruction via C-end degrons pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation. The C-degron recognized by the DesCEND pathway is usually a motif of less than ten residues and can be present in full-length proteins, truncated proteins or proteolytically cleaved forms. The CRL2(KLHDC2 complex specifically recognizes proteins with a diglycine (Gly-Gly at the C-terminus, leading to their ubiquitination and degradation. The CRL2(KLHDC2 complex mediates ubiquitination and degradation of truncated SELENOK and SELENOS selenoproteins produced by failed UGA/Sec decoding, which end with a diglycine. The CRL2(KLHDC2 complex also recognizes proteolytically cleaved proteins ending with Gly-Gly, such as the N-terminal fragment of USP1, leading to their degradation. May also act as an indirect repressor of CREB3-mediated transcription by interfering with CREB3-DNA-binding.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human KLHDC2 (NP_055130.1).
PurificationAffinity purification
Gene ID23588
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000

All Names

AlternameKLHDC2; HCLP-1; HCLP1; LCP
📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Certificate of Analysis (PDF)🧪MSDS
Material safety data sheet (PDF)

Conjugated Antibody

This product is also available conjugated. Format: E45R21698N-Conjugate. Price: $485 / Size: 100μl.

E45R21698N-FITC$485 / 100μlE45R21698N-Biotin$485 / 100μlE45R21698N-HRP$485 / 100μlE45R21698N-AP$485 / 100μlE45R21698N-AF350$485 / 100μlE45R21698N-AF405M$485 / 100μlE45R21698N-AF488$485 / 100μlE45R21698N-AF514$485 / 100μlE45R21698N-AF532$485 / 100μlE45R21698N-AF555$485 / 100μlE45R21698N-AF568$485 / 100μlE45R21698N-AF405S$485 / 100μlE45R21698N-AF405L$485 / 100μlE45R21698N-AF546$485 / 100μlE45R21698N-AF594$485 / 100μlE45R21698N-AF610$485 / 100μlE45R21698N-AF635$485 / 100μlE45R21698N-AF647$485 / 100μlE45R21698N-AF680$485 / 100μlE45R21698N-AF700$485 / 100μlE45R21698N-AF750$485 / 100μlE45R21698N-AF790$485 / 100μlE45R21698N-APC$485 / 100μlE45R21698N-PE$485 / 100μlE45R21698N-Cy3$485 / 100μlE45R21698N-Cy5$485 / 100μlE45R21698N-Cy5.5$485 / 100μlE45R21698N-Cy7$485 / 100μlE45R21698N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

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KLHDC2 Rabbit pAb | EnoGene Biotech Co. Ltd