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ABI2 Rabbit pAb
Human, Mouse
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5509253
TypePolyclonal Antibodies
HostRabbit
Positive controlU-251MG, Mouse brain
IsotypeIgG
SummaryRegulator of actin cytoskeleton dynamics underlying cell motility and adhesion. Functions as a component of the WAVE complex, which activates actin nucleating machinery Arp2/3 to drive lamellipodia formation. Acts as regulator and substrate of nonreceptor tyrosine kinases ABL1 and ABL2 involved in processes linked to cell growth and differentiation. Positively regulates ABL1-mediated phosphorylation of ENAH, which is required for proper polymerization of nucleated actin filaments at the leading edge. Contributes to the regulation of actin assembly at the tips of neuron projections. In particular, controls dendritic spine morphogenesis and may promote dendritic spine specification toward large mushroom-type spines known as repositories of memory in the brain (By similarity. In hippocampal neurons, may mediate actin-dependent BDNF-NTRK2 early endocytic trafficking that triggers dendrite outgrowth (By similarity. Participates in ocular lens morphogenesis, likely by regulating lamellipodia-driven adherens junction formation at the epithelial cell-secondary lens fiber interface (By similarity. Also required for nascent adherens junction assembly in epithelial cells.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 100-200 of human ABI2 (NP_001269854.1).
PurificationAffinity purification
Gene ID10152
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
All Names
AlternameABI2; ABI-2; ABI2B; AIP-1; AblBP3; SSH3BP2; argBP1; argBPIA; argBPIB
Conjugated Antibody
This product is also available conjugated. Format: E45R21544N-Conjugate. Price: $485 / Size: 100μl.
E45R21544N-FITC$485 / 100μlE45R21544N-Biotin$485 / 100μlE45R21544N-HRP$485 / 100μlE45R21544N-AP$485 / 100μlE45R21544N-AF350$485 / 100μlE45R21544N-AF405M$485 / 100μlE45R21544N-AF488$485 / 100μlE45R21544N-AF514$485 / 100μlE45R21544N-AF532$485 / 100μlE45R21544N-AF555$485 / 100μlE45R21544N-AF568$485 / 100μlE45R21544N-AF405S$485 / 100μlE45R21544N-AF405L$485 / 100μlE45R21544N-AF546$485 / 100μlE45R21544N-AF594$485 / 100μlE45R21544N-AF610$485 / 100μlE45R21544N-AF635$485 / 100μlE45R21544N-AF647$485 / 100μlE45R21544N-AF680$485 / 100μlE45R21544N-AF700$485 / 100μlE45R21544N-AF750$485 / 100μlE45R21544N-AF790$485 / 100μlE45R21544N-APC$485 / 100μlE45R21544N-PE$485 / 100μlE45R21544N-Cy3$485 / 100μlE45R21544N-Cy5$485 / 100μlE45R21544N-Cy5.5$485 / 100μlE45R21544N-Cy7$485 / 100μlE45R21544N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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