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PDP1 Rabbit pAb
Human, Mouse, Rat
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5508941
TypePolyclonal Antibodies
HostRabbit
Positive control293T, U-87MG, DU145, 5637, mouse brain, mouse skeletal muscle, mouse heart, rat skeletal muscle, rat heart
IsotypeIgG
SummaryPyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits. Two catalytic subunits have been reported; one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver. The catalytic subunit, encoded by this gene, is the former, and belongs to the protein phosphatase 2C (PP2C) superfamily. Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases, this enzyme is located in the mitochondrial matrix. Mutation in this gene causes pyruvate dehydrogenase phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 72-260 of human PDP1 (NP_060914.2).
PurificationAffinity purification
Gene ID54704
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IF 1:50 - 1:200
IF 1:50 - 1:200
All Names
AlternamePDP1; PDH; PDP; PDPC; PPM2A; PPM2C
Conjugated Antibody
This product is also available conjugated. Format: E45R21102N-Conjugate. Price: $485 / Size: 100μl.
E45R21102N-FITC$485 / 100μlE45R21102N-Biotin$485 / 100μlE45R21102N-HRP$485 / 100μlE45R21102N-AP$485 / 100μlE45R21102N-AF350$485 / 100μlE45R21102N-AF405M$485 / 100μlE45R21102N-AF488$485 / 100μlE45R21102N-AF514$485 / 100μlE45R21102N-AF532$485 / 100μlE45R21102N-AF555$485 / 100μlE45R21102N-AF568$485 / 100μlE45R21102N-AF405S$485 / 100μlE45R21102N-AF405L$485 / 100μlE45R21102N-AF546$485 / 100μlE45R21102N-AF594$485 / 100μlE45R21102N-AF610$485 / 100μlE45R21102N-AF635$485 / 100μlE45R21102N-AF647$485 / 100μlE45R21102N-AF680$485 / 100μlE45R21102N-AF700$485 / 100μlE45R21102N-AF750$485 / 100μlE45R21102N-AF790$485 / 100μlE45R21102N-APC$485 / 100μlE45R21102N-PE$485 / 100μlE45R21102N-Cy3$485 / 100μlE45R21102N-Cy5$485 / 100μlE45R21102N-Cy5.5$485 / 100μlE45R21102N-Cy7$485 / 100μlE45R21102N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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