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CDK5R1 Rabbit pAb

E45R21052NDatasheetCOAMSDS
Human, Mouse, Rat
Q15078
$409/ 100 µl
Quantity
Total: $409

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5516129
TypePolyclonal Antibodies
HostRabbit
Positive controlMouse brain, Rat brain
IsotypeIgG
SummaryThe protein encoded by this gene (p35) is a neuron-specific activator of cyclin-dependent kinase 5 (CDK5); the activation of CDK5 is required for proper development of the central nervous system. The p35 form of this protein is proteolytically cleaved by calpain, generating a p25 form. The cleavage of p35 into p25 results in relocalization of the protein from the cell periphery to nuclear and perinuclear regions. P25 deregulates CDK5 activity by prolonging its activation and changing its cellular location. The p25 form accumulates in the brain neurons of patients with Alzheimer's disease. This accumulation correlates with an increase in CDK5 kinase activity, and may lead to aberrantly phosphorylated forms of the microtubule-associated protein tau, which contributes to Alzheimer's disease.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 99-307 of human CDK5R1 (NP_003876.1).
PurificationAffinity purification
Gene ID8851
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IF 1:50 - 1:200

All Names

AlternameCDK5R1; CDK5P35; CDK5R; NCK5A; p23; p25; p35; p35nck5a
📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Certificate of Analysis (PDF)🧪MSDS
Material safety data sheet (PDF)

Conjugated Antibody

This product is also available conjugated. Format: E45R21052N-Conjugate. Price: $485 / Size: 100μl.

E45R21052N-FITC$485 / 100μlE45R21052N-Biotin$485 / 100μlE45R21052N-HRP$485 / 100μlE45R21052N-AP$485 / 100μlE45R21052N-AF350$485 / 100μlE45R21052N-AF405M$485 / 100μlE45R21052N-AF488$485 / 100μlE45R21052N-AF514$485 / 100μlE45R21052N-AF532$485 / 100μlE45R21052N-AF555$485 / 100μlE45R21052N-AF568$485 / 100μlE45R21052N-AF405S$485 / 100μlE45R21052N-AF405L$485 / 100μlE45R21052N-AF546$485 / 100μlE45R21052N-AF594$485 / 100μlE45R21052N-AF610$485 / 100μlE45R21052N-AF635$485 / 100μlE45R21052N-AF647$485 / 100μlE45R21052N-AF680$485 / 100μlE45R21052N-AF700$485 / 100μlE45R21052N-AF750$485 / 100μlE45R21052N-AF790$485 / 100μlE45R21052N-APC$485 / 100μlE45R21052N-PE$485 / 100μlE45R21052N-Cy3$485 / 100μlE45R21052N-Cy5$485 / 100μlE45R21052N-Cy5.5$485 / 100μlE45R21052N-Cy7$485 / 100μlE45R21052N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

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CDK5R1 Rabbit pAb | EnoGene Biotech Co. Ltd