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NLRP3 Rabbit pAb
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5505465
TypePolyclonal Antibodies
HostRabbit
Positive controlRat lung
IsotypeIgG
SummaryThis gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are suggested by available data; however, insufficient evidence is available to determine if all of the represented 5' UTR splice patterns are biologically valid.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant protein of human NLRP3
PurificationAffinity purification
Gene ID114548
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:200 - 1:1000
IF 1:20 - 1:200
IF 1:20 - 1:200
All Names
AlternameNLRP3; AGTAVPRL; AII; AVP; C1orf7; CIAS1; CLR1.1; FCAS; FCAS1; FCU; MWS; NALP3; PYPAF1
Conjugated Antibody
This product is also available conjugated. Format: E45R20773N-Conjugate. Price: $485 / Size: 100μl.
E45R20773N-FITC$485 / 100μlE45R20773N-Biotin$485 / 100μlE45R20773N-HRP$485 / 100μlE45R20773N-AP$485 / 100μlE45R20773N-AF350$485 / 100μlE45R20773N-AF405M$485 / 100μlE45R20773N-AF488$485 / 100μlE45R20773N-AF514$485 / 100μlE45R20773N-AF532$485 / 100μlE45R20773N-AF555$485 / 100μlE45R20773N-AF568$485 / 100μlE45R20773N-AF405S$485 / 100μlE45R20773N-AF405L$485 / 100μlE45R20773N-AF546$485 / 100μlE45R20773N-AF594$485 / 100μlE45R20773N-AF610$485 / 100μlE45R20773N-AF635$485 / 100μlE45R20773N-AF647$485 / 100μlE45R20773N-AF680$485 / 100μlE45R20773N-AF700$485 / 100μlE45R20773N-AF750$485 / 100μlE45R20773N-AF790$485 / 100μlE45R20773N-APC$485 / 100μlE45R20773N-PE$485 / 100μlE45R20773N-Cy3$485 / 100μlE45R20773N-Cy5$485 / 100μlE45R20773N-Cy5.5$485 / 100μlE45R20773N-Cy7$485 / 100μlE45R20773N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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