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CRYAB Rabbit pAb
Human, Mouse, Rat
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5508432
TypePolyclonal Antibodies
HostRabbit
Positive controlU-87MG, 293T, A-549, Mouse brain, Mouse heart, Mouse kidney, Mouse lung, Rat heart
IsotypeIgG
SummaryMammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Alpha-A and alpha-B gene products are differentially expressed; alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases; a missense mutation cosegregated in a family with a desmin-related myopathy. Alternative splicing results in multiple transcript variants.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-175 of human CRYAB (NP_001876.1).
PurificationAffinity purification
Gene ID1410
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
All Names
AlternameCRYAB; CMD1II; CRYA2; CTPP2; CTRCT16; HEL-S-101; HSPB5; MFM2
Conjugated Antibody
This product is also available conjugated. Format: E45R20267N-Conjugate. Price: $485 / Size: 100μl.
E45R20267N-FITC$485 / 100μlE45R20267N-Biotin$485 / 100μlE45R20267N-HRP$485 / 100μlE45R20267N-AP$485 / 100μlE45R20267N-AF350$485 / 100μlE45R20267N-AF405M$485 / 100μlE45R20267N-AF488$485 / 100μlE45R20267N-AF514$485 / 100μlE45R20267N-AF532$485 / 100μlE45R20267N-AF555$485 / 100μlE45R20267N-AF568$485 / 100μlE45R20267N-AF405S$485 / 100μlE45R20267N-AF405L$485 / 100μlE45R20267N-AF546$485 / 100μlE45R20267N-AF594$485 / 100μlE45R20267N-AF610$485 / 100μlE45R20267N-AF635$485 / 100μlE45R20267N-AF647$485 / 100μlE45R20267N-AF680$485 / 100μlE45R20267N-AF700$485 / 100μlE45R20267N-AF750$485 / 100μlE45R20267N-AF790$485 / 100μlE45R20267N-APC$485 / 100μlE45R20267N-PE$485 / 100μlE45R20267N-Cy3$485 / 100μlE45R20267N-Cy5$485 / 100μlE45R20267N-Cy5.5$485 / 100μlE45R20267N-Cy7$485 / 100μlE45R20267N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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