Catalog Number:
E45R20249NAmount:
100 µlCite ID#:
EN5508444Price:
409$Type:
Polyclonal AntibodiesHost:
RabbitReactivity:
HumanImmunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 137-426 of human IRF8 (NP_002154.1).Positive control:
THP-1Isotype:
IgGPurification:
Affinity purificationGene ID:
3394Swiss-Prot No.:
Q02556Summary:
Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.Form:
LiquidStorage/Stability:
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.Dilution:
WB 1:500 - 1:2000Altername:
IRF8; H-ICSBP; ICSBP; ICSBP1; IMD32A; IMD32B; IRF-8