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FAT10/UBD Rabbit pAb

Human, Mouse, Rat
O15205
$409/ 100 µl
Quantity
Total: $409

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5508268
TypePolyclonal Antibodies
HostRabbit
IsotypeIgG
SummaryUbiquitin-like protein modifier which can be covalently attached to target protein and subsequently leads to their degradation by the 26S proteasome, in a NUB1-dependent manner. Probably functions as a survival factor. Conjugation ability activated by UBA6. Promotes the expression of the proteasome subunit beta type-9 (PSMB9/LMP2. Regulates TNF-alpha-induced and LPS-mediated activation of the central mediator of innate immunity NF-kappa-B by promoting TNF-alpha-mediated proteasomal degradation of ubiquitinated-I-kappa-B-alpha. Required for TNF-alpha-induced p65 nuclear translocation in renal tubular epithelial cells (RTECs. May be involved in dendritic cell (DC maturation, the process by which immature dendritic cells differentiate into fully competent antigen-presenting cells that initiate T-cell responses. Mediates mitotic non-disjunction and chromosome instability, in long-term in vitro culture and cancers, by abbreviating mitotic phase and impairing the kinetochore localization of MAD2L1 during the prometaphase stage of the cell cycle. May be involved in the formation of aggresomes when proteasome is saturated or impaired. Mediates apoptosis in a caspase-dependent manner, especially in renal epithelium and tubular cells during renal diseases such as polycystic kidney disease and Human immunodeficiency virus (HIV-associated nephropathy (HIVAN.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human FAT10/FAT10/UBD (NP_006389.2).
PurificationAffinity purification
Gene ID10537
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionIHC 1:50 - 1:200
IF 1:50 - 1:200

All Names

AlternameUBD; FAT10; GABBR1; UBD-3

Conjugated Antibody

This product is also available conjugated. Format: E45R19989N-Conjugate. Price: $485 / Size: 100μl.

E45R19989N-FITC$485 / 100μlE45R19989N-Biotin$485 / 100μlE45R19989N-HRP$485 / 100μlE45R19989N-AP$485 / 100μlE45R19989N-AF350$485 / 100μlE45R19989N-AF405M$485 / 100μlE45R19989N-AF488$485 / 100μlE45R19989N-AF514$485 / 100μlE45R19989N-AF532$485 / 100μlE45R19989N-AF555$485 / 100μlE45R19989N-AF568$485 / 100μlE45R19989N-AF405S$485 / 100μlE45R19989N-AF405L$485 / 100μlE45R19989N-AF546$485 / 100μlE45R19989N-AF594$485 / 100μlE45R19989N-AF610$485 / 100μlE45R19989N-AF635$485 / 100μlE45R19989N-AF647$485 / 100μlE45R19989N-AF680$485 / 100μlE45R19989N-AF700$485 / 100μlE45R19989N-AF750$485 / 100μlE45R19989N-AF790$485 / 100μlE45R19989N-APC$485 / 100μlE45R19989N-PE$485 / 100μlE45R19989N-Cy3$485 / 100μlE45R19989N-Cy5$485 / 100μlE45R19989N-Cy5.5$485 / 100μlE45R19989N-Cy7$485 / 100μlE45R19989N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.