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SKIV2L2 Rabbit pAb
Human, Mouse, Rat
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5508112
TypePolyclonal Antibodies
HostRabbit
Positive control293T, HeLa, U-87MG, NIH/3T3, Mouse brain, Mouse testis, Rat testis
IsotypeIgG
SummaryCatalyzes the ATP-dependent unwinding of RNA duplexes with a single-stranded 3' RNA extension. Central subunit of many protein complexes, namely TRAMP-like, nuclear exosome targeting (NEXT and poly(A tail exosome targeting (PAXT. NEXT functions as an RNA exosome cofactor that directs a subset of non-coding short-lived RNAs for exosomal degradation. NEXT is involved in surveillance and turnover of aberrant transcripts and non-coding RNAs. PAXT directs a subset of long and polyadenylated poly(A RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor ZCCHC8, which links to RNA-binding protein adapters. Associated with the RNA exosome complex and involved in the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA. May be involved in pre-mRNA splicing. In the context of NEXT complex can also in vitro unwind DNA:RNA heteroduplexes with a 3' poly (A RNA tracking strand. Can promote unwinding and degradation of structured RNA substrates when associated with the nuclear exosome and its cofactors. Can displace a DNA strand while translocating on RNA to ultimately degrade the RNA within a DNA/RNA heteroduplex. Plays a role in DNA damage response.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SKIV2L2 (NP_056175.3).
PurificationAffinity purification
Gene ID23517
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
All Names
AlternameSKIV2L2; Dob1; KIAA0052; Mtr4; fSAP118
Conjugated Antibody
This product is also available conjugated. Format: E45R19856N-Conjugate. Price: $485 / Size: 100μl.
E45R19856N-FITC$485 / 100μlE45R19856N-Biotin$485 / 100μlE45R19856N-HRP$485 / 100μlE45R19856N-AP$485 / 100μlE45R19856N-AF350$485 / 100μlE45R19856N-AF405M$485 / 100μlE45R19856N-AF488$485 / 100μlE45R19856N-AF514$485 / 100μlE45R19856N-AF532$485 / 100μlE45R19856N-AF555$485 / 100μlE45R19856N-AF568$485 / 100μlE45R19856N-AF405S$485 / 100μlE45R19856N-AF405L$485 / 100μlE45R19856N-AF546$485 / 100μlE45R19856N-AF594$485 / 100μlE45R19856N-AF610$485 / 100μlE45R19856N-AF635$485 / 100μlE45R19856N-AF647$485 / 100μlE45R19856N-AF680$485 / 100μlE45R19856N-AF700$485 / 100μlE45R19856N-AF750$485 / 100μlE45R19856N-AF790$485 / 100μlE45R19856N-APC$485 / 100μlE45R19856N-PE$485 / 100μlE45R19856N-Cy3$485 / 100μlE45R19856N-Cy5$485 / 100μlE45R19856N-Cy5.5$485 / 100μlE45R19856N-Cy7$485 / 100μlE45R19856N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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