Product Information
Cite ID#EN5508051
TypePolyclonal Antibodies
HostRabbit
Positive controlMCF7, SW480, Jurkat, A-549, DU145, Mouse brain, Mouse liver
IsotypeIgG
SummaryMachado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.