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HLA-DRB5 Rabbit pAb

E45R19351NDatasheetCOAMSDS
Human
Q30154
$409/ 100 µl
Quantity
Total: $409

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5507784
TypePolyclonal Antibodies
HostRabbit
Positive controlHeLa, Raji
IsotypeIgG
SummaryHLA-DRB5 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5. The presence of DRB5 is linked with allelic variants of DRB1, otherwise it is omitted. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 30-227 of human HLA-DRB5 (NP_002116.2).
PurificationAffinity purification
Gene ID3127
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:1000 - 1:2000

All Names

AlternameHLA-DRB5; HLA-DRB; major histocompatibility complex; class II; DR beta 5
📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Certificate of Analysis (PDF)🧪MSDS
Material safety data sheet (PDF)

Conjugated Antibody

This product is also available conjugated. Format: E45R19351N-Conjugate. Price: $485 / Size: 100μl.

E45R19351N-FITC$485 / 100μlE45R19351N-Biotin$485 / 100μlE45R19351N-HRP$485 / 100μlE45R19351N-AP$485 / 100μlE45R19351N-AF350$485 / 100μlE45R19351N-AF405M$485 / 100μlE45R19351N-AF488$485 / 100μlE45R19351N-AF514$485 / 100μlE45R19351N-AF532$485 / 100μlE45R19351N-AF555$485 / 100μlE45R19351N-AF568$485 / 100μlE45R19351N-AF405S$485 / 100μlE45R19351N-AF405L$485 / 100μlE45R19351N-AF546$485 / 100μlE45R19351N-AF594$485 / 100μlE45R19351N-AF610$485 / 100μlE45R19351N-AF635$485 / 100μlE45R19351N-AF647$485 / 100μlE45R19351N-AF680$485 / 100μlE45R19351N-AF700$485 / 100μlE45R19351N-AF750$485 / 100μlE45R19351N-AF790$485 / 100μlE45R19351N-APC$485 / 100μlE45R19351N-PE$485 / 100μlE45R19351N-Cy3$485 / 100μlE45R19351N-Cy5$485 / 100μlE45R19351N-Cy5.5$485 / 100μlE45R19351N-Cy7$485 / 100μlE45R19351N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

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HLA-DRB5 Rabbit pAb | EnoGene Biotech Co. Ltd