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NLRP3 Rabbit pAb
Human, Mouse, Rat
IF (Mouse colon cancer cells, Mus musculus, Gallus gallus, Rattus norvegicus)
WB (Mouse colon cancer cells, Mus musculus, Rattus norvegicus, Gallus gallus, Homo sapiens)
IHC (Mus musculus, Rattus norvegicus)
WB (Mouse colon cancer cells, Mus musculus, Rattus norvegicus, Gallus gallus, Homo sapiens)
IHC (Mus musculus, Rattus norvegicus)
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5515960
TypePolyclonal Antibodies
HostRabbit
Positive controlRaji, RAW264.7
IsotypeIgG
SummaryThis gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are suggested by available data; however, insufficient evidence is available to determine if all of the represented 5' UTR splice patterns are biologically valid.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 900 to the C-terminus of human NLRP3 (NP_001120934.1).
PurificationAffinity purification
Gene ID114548
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:1000 - 1:3000
IHC 1:50 - 1:200
IF 1:50 - 1:200
IHC 1:50 - 1:200
IF 1:50 - 1:200
All Names
AlternameNLRP3; AGTAVPRL; AII; AVP; C1orf7; CIAS1; CLR1.1; FCAS; FCAS1; FCU; MWS; NALP3; PYPAF1
Conjugated Antibody
This product is also available conjugated. Format: E45R19319N-Conjugate. Price: $485 / Size: 100μl.
E45R19319N-FITC$485 / 100μlE45R19319N-Biotin$485 / 100μlE45R19319N-HRP$485 / 100μlE45R19319N-AP$485 / 100μlE45R19319N-AF350$485 / 100μlE45R19319N-AF405M$485 / 100μlE45R19319N-AF488$485 / 100μlE45R19319N-AF514$485 / 100μlE45R19319N-AF532$485 / 100μlE45R19319N-AF555$485 / 100μlE45R19319N-AF568$485 / 100μlE45R19319N-AF405S$485 / 100μlE45R19319N-AF405L$485 / 100μlE45R19319N-AF546$485 / 100μlE45R19319N-AF594$485 / 100μlE45R19319N-AF610$485 / 100μlE45R19319N-AF635$485 / 100μlE45R19319N-AF647$485 / 100μlE45R19319N-AF680$485 / 100μlE45R19319N-AF700$485 / 100μlE45R19319N-AF750$485 / 100μlE45R19319N-AF790$485 / 100μlE45R19319N-APC$485 / 100μlE45R19319N-PE$485 / 100μlE45R19319N-Cy3$485 / 100μlE45R19319N-Cy5$485 / 100μlE45R19319N-Cy5.5$485 / 100μlE45R19319N-Cy7$485 / 100μlE45R19319N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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