Product Information
Cite ID#EN5507472
TypePolyclonal Antibodies
HostRabbit
Positive controlBxPC-3, HepG2, 293T, Mouse kidney, Mouse liver, Mouse heart, Rat kidney
IsotypeIgG
SummaryThe protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.