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PAX5 Rabbit pAb
Human, Rat
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5507448
TypePolyclonal Antibodies
HostRabbit
Positive controlK-562, Raji, A-549, Rat heart
IsotypeIgG
SummaryThis gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. Paired box transcription factors are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternative splicing results in multiple transcript variants encoding different isoforms.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 1-100 of human PAX5 (NP_057953.1).
PurificationAffinity purification
Gene ID5079
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
All Names
AlternamePAX5; ALL3; BSAP
Conjugated Antibody
This product is also available conjugated. Format: E45R18750N-Conjugate. Price: $485 / Size: 100μl.
E45R18750N-FITC$485 / 100μlE45R18750N-Biotin$485 / 100μlE45R18750N-HRP$485 / 100μlE45R18750N-AP$485 / 100μlE45R18750N-AF350$485 / 100μlE45R18750N-AF405M$485 / 100μlE45R18750N-AF488$485 / 100μlE45R18750N-AF514$485 / 100μlE45R18750N-AF532$485 / 100μlE45R18750N-AF555$485 / 100μlE45R18750N-AF568$485 / 100μlE45R18750N-AF405S$485 / 100μlE45R18750N-AF405L$485 / 100μlE45R18750N-AF546$485 / 100μlE45R18750N-AF594$485 / 100μlE45R18750N-AF610$485 / 100μlE45R18750N-AF635$485 / 100μlE45R18750N-AF647$485 / 100μlE45R18750N-AF680$485 / 100μlE45R18750N-AF700$485 / 100μlE45R18750N-AF750$485 / 100μlE45R18750N-AF790$485 / 100μlE45R18750N-APC$485 / 100μlE45R18750N-PE$485 / 100μlE45R18750N-Cy3$485 / 100μlE45R18750N-Cy5$485 / 100μlE45R18750N-Cy5.5$485 / 100μlE45R18750N-Cy7$485 / 100μlE45R18750N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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