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KLRK1 Rabbit pAb
Human
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5507330
TypePolyclonal Antibodies
HostRabbit
IsotypeIgG
SummaryNatural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. This gene encodes a member of the NKG2 family. The encoded transmembrane protein is characterized by a type II membrane orientation (has an extracellular C terminus) and the presence of a C-type lectin domain. It binds to a diverse family of ligands that include MHC class I chain-related A and B proteins and UL-16 binding proteins, where ligand-receptor interactions can result in the activation of NK and T cells. The surface expression of these ligands is important for the recognition of stressed cells by the immune system, and thus this protein and its ligands are therapeutic targets for the treatment of immune diseases and cancers. Read-through transcription exists between this gene and the upstream KLRC4 (killer cell lectin-like receptor subfamily C, member 4) family member in the same cluster.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 50-150 of human KLRK1 (NP_031386.2).
PurificationAffinity purification
Gene ID22914
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionIF 1:50 - 1:200
All Names
AlternameKLRK1; CD314; D12S2489E; KLR; NKG2-D; NKG2D
Conjugated Antibody
This product is also available conjugated. Format: E45R18691N-Conjugate. Price: $485 / Size: 100μl.
E45R18691N-FITC$485 / 100μlE45R18691N-Biotin$485 / 100μlE45R18691N-HRP$485 / 100μlE45R18691N-AP$485 / 100μlE45R18691N-AF350$485 / 100μlE45R18691N-AF405M$485 / 100μlE45R18691N-AF488$485 / 100μlE45R18691N-AF514$485 / 100μlE45R18691N-AF532$485 / 100μlE45R18691N-AF555$485 / 100μlE45R18691N-AF568$485 / 100μlE45R18691N-AF405S$485 / 100μlE45R18691N-AF405L$485 / 100μlE45R18691N-AF546$485 / 100μlE45R18691N-AF594$485 / 100μlE45R18691N-AF610$485 / 100μlE45R18691N-AF635$485 / 100μlE45R18691N-AF647$485 / 100μlE45R18691N-AF680$485 / 100μlE45R18691N-AF700$485 / 100μlE45R18691N-AF750$485 / 100μlE45R18691N-AF790$485 / 100μlE45R18691N-APC$485 / 100μlE45R18691N-PE$485 / 100μlE45R18691N-Cy3$485 / 100μlE45R18691N-Cy5$485 / 100μlE45R18691N-Cy5.5$485 / 100μlE45R18691N-Cy7$485 / 100μlE45R18691N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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