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SHARPIN Rabbit pAb
Human, Rat
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5507339
TypePolyclonal Antibodies
HostRabbit
Positive control293T, LO2, HeLa, A-549, Rat brain
IsotypeIgG
SummaryComponent of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is recruited to the TNF-R1 signaling complex (TNF-RSC following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. Together with OTULIN, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human SHARPIN (NP_112236.3).
PurificationAffinity purification
Gene ID81858
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
All Names
AlternameSHARPIN; SIPL1; sharpin
Conjugated Antibody
This product is also available conjugated. Format: E45R18603N-Conjugate. Price: $485 / Size: 100μl.
E45R18603N-FITC$485 / 100μlE45R18603N-Biotin$485 / 100μlE45R18603N-HRP$485 / 100μlE45R18603N-AP$485 / 100μlE45R18603N-AF350$485 / 100μlE45R18603N-AF405M$485 / 100μlE45R18603N-AF488$485 / 100μlE45R18603N-AF514$485 / 100μlE45R18603N-AF532$485 / 100μlE45R18603N-AF555$485 / 100μlE45R18603N-AF568$485 / 100μlE45R18603N-AF405S$485 / 100μlE45R18603N-AF405L$485 / 100μlE45R18603N-AF546$485 / 100μlE45R18603N-AF594$485 / 100μlE45R18603N-AF610$485 / 100μlE45R18603N-AF635$485 / 100μlE45R18603N-AF647$485 / 100μlE45R18603N-AF680$485 / 100μlE45R18603N-AF700$485 / 100μlE45R18603N-AF750$485 / 100μlE45R18603N-AF790$485 / 100μlE45R18603N-APC$485 / 100μlE45R18603N-PE$485 / 100μlE45R18603N-Cy3$485 / 100μlE45R18603N-Cy5$485 / 100μlE45R18603N-Cy5.5$485 / 100μlE45R18603N-Cy7$485 / 100μlE45R18603N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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