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CDKN1A/p21CIP1 Rabbit pAb
Human, Mouse, Rat
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5507279
TypePolyclonal Antibodies
HostRabbit
Positive controlMCF7
IsotypeIgG
SummaryThis gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-cyclin-dependent kinase2 or -cyclin-dependent kinase4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen, a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of cyclin-dependent kinase2, and may be instrumental in the execution of apoptosis following caspase activation. Mice that lack this gene have the ability to regenerate damaged or missing tissue. Multiple alternatively spliced variants have been found for this gene.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-164 of human CDKN1A/p21CIP1 (NP_001207707.1).
PurificationAffinity purification
Gene ID1026
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
IP 1:50 - 1:200
IHC 1:50 - 1:200
IF 1:50 - 1:200
IP 1:50 - 1:200
All Names
AlternameCAP20; CDKN1; CIP1; MDA-6; P21; SDI1; WAF1; p21CIP1; CDKN1A
Conjugated Antibody
This product is also available conjugated. Format: E45R18463N-Conjugate. Price: $485 / Size: 100μl.
E45R18463N-FITC$485 / 100μlE45R18463N-Biotin$485 / 100μlE45R18463N-HRP$485 / 100μlE45R18463N-AP$485 / 100μlE45R18463N-AF350$485 / 100μlE45R18463N-AF405M$485 / 100μlE45R18463N-AF488$485 / 100μlE45R18463N-AF514$485 / 100μlE45R18463N-AF532$485 / 100μlE45R18463N-AF555$485 / 100μlE45R18463N-AF568$485 / 100μlE45R18463N-AF405S$485 / 100μlE45R18463N-AF405L$485 / 100μlE45R18463N-AF546$485 / 100μlE45R18463N-AF594$485 / 100μlE45R18463N-AF610$485 / 100μlE45R18463N-AF635$485 / 100μlE45R18463N-AF647$485 / 100μlE45R18463N-AF680$485 / 100μlE45R18463N-AF700$485 / 100μlE45R18463N-AF750$485 / 100μlE45R18463N-AF790$485 / 100μlE45R18463N-APC$485 / 100μlE45R18463N-PE$485 / 100μlE45R18463N-Cy3$485 / 100μlE45R18463N-Cy5$485 / 100μlE45R18463N-Cy5.5$485 / 100μlE45R18463N-Cy7$485 / 100μlE45R18463N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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