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SH2D1A Rabbit pAb

Human, Mouse
O60880
$409/ 100 µl
Quantity
Total: $409

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5507266
TypePolyclonal Antibodies
HostRabbit
Positive controlJurkat, PC-3, Mouse spleen
IsotypeIgG
SummaryThis gene encodes a protein that plays a major role in the bidirectional stimulation of T and B cells. This protein contains an SH2 domain and a short tail. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in this gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-128 of human SH2D1A (NP_002342.1).
PurificationAffinity purification
Gene ID4068
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
IF 1:50 - 1:200

All Names

AlternameSH2D1A; DSHP; EBVS; IMD5; LYP; MTCP1; SAP; SAP/SH2D1A; XLP; XLPD; XLPD1

Conjugated Antibody

This product is also available conjugated. Format: E45R18453N-Conjugate. Price: $485 / Size: 100μl.

E45R18453N-FITC$485 / 100μlE45R18453N-Biotin$485 / 100μlE45R18453N-HRP$485 / 100μlE45R18453N-AP$485 / 100μlE45R18453N-AF350$485 / 100μlE45R18453N-AF405M$485 / 100μlE45R18453N-AF488$485 / 100μlE45R18453N-AF514$485 / 100μlE45R18453N-AF532$485 / 100μlE45R18453N-AF555$485 / 100μlE45R18453N-AF568$485 / 100μlE45R18453N-AF405S$485 / 100μlE45R18453N-AF405L$485 / 100μlE45R18453N-AF546$485 / 100μlE45R18453N-AF594$485 / 100μlE45R18453N-AF610$485 / 100μlE45R18453N-AF635$485 / 100μlE45R18453N-AF647$485 / 100μlE45R18453N-AF680$485 / 100μlE45R18453N-AF700$485 / 100μlE45R18453N-AF750$485 / 100μlE45R18453N-AF790$485 / 100μlE45R18453N-APC$485 / 100μlE45R18453N-PE$485 / 100μlE45R18453N-Cy3$485 / 100μlE45R18453N-Cy5$485 / 100μlE45R18453N-Cy5.5$485 / 100μlE45R18453N-Cy7$485 / 100μlE45R18453N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

SH2D1A Rabbit pAb | EnoGene Biotech Co. Ltd