Product Information
Cite ID#EN5516280
TypePolyclonal Antibodies
HostRabbit
Positive controlHT-29
IsotypeIgG
SummaryThe protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human AMPKα1 (NP_006242.5).
PurificationAffinity purification
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
All Names
AlternamePRKAA1; AMPK; AMPKa1