Product Information
Cite ID#EN5516411
TypePolyclonal Antibodies
HostRabbit
Positive controlHepG2, Jurkat, Mouse liver, Mouse kidney, Mouse heart, Rat kidney, Rat heart
IsotypeIgG
SummaryComplex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.