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LAPTM4B Rabbit pAb

E45R18262NDatasheetCOAMSDS
Human, Mouse, Rat
Q86VI4
$409/ 100 µl
Quantity
Total: $409

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5507196
TypePolyclonal Antibodies
HostRabbit
Positive controlU-87MG, HeLa, A-549, SKOV3, B cells, Mouse brain, Mouse eye, Rat ovary
IsotypeIgG
SummaryRequired for optimal lysosomal function. Blocks EGF-stimulated EGFR intraluminal sorting and degradation. Conversely by binding with the phosphatidylinositol 4,5-bisphosphate, regulates its PIP5K1C interaction, inhibits HGS ubiquitination and relieves LAPTM4B inhibition of EGFR degradation. Recruits SLC3A2 and SLC7A5 (the Leu transporter to the lysosome, promoting entry of leucine and other essential amino acid (EAA into the lysosome, stimulating activation of proton-transporting vacuolar (V-ATPase protein pump (V-ATPase and hence mTORC1 activation. Plays a role as negative regulator of TGFB1 production in regulatory T cells. Binds ceramide and facilitates its exit from late endosome in order to control cell death pathways.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 218-317 of human LAPTM4B (NP_060877.3).
PurificationAffinity purification
Gene ID55353
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000

All Names

AlternameLAPTM4B; LAPTM4beta; LC27
📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Certificate of Analysis (PDF)🧪MSDS
Material safety data sheet (PDF)

Conjugated Antibody

This product is also available conjugated. Format: E45R18262N-Conjugate. Price: $485 / Size: 100μl.

E45R18262N-FITC$485 / 100μlE45R18262N-Biotin$485 / 100μlE45R18262N-HRP$485 / 100μlE45R18262N-AP$485 / 100μlE45R18262N-AF350$485 / 100μlE45R18262N-AF405M$485 / 100μlE45R18262N-AF488$485 / 100μlE45R18262N-AF514$485 / 100μlE45R18262N-AF532$485 / 100μlE45R18262N-AF555$485 / 100μlE45R18262N-AF568$485 / 100μlE45R18262N-AF405S$485 / 100μlE45R18262N-AF405L$485 / 100μlE45R18262N-AF546$485 / 100μlE45R18262N-AF594$485 / 100μlE45R18262N-AF610$485 / 100μlE45R18262N-AF635$485 / 100μlE45R18262N-AF647$485 / 100μlE45R18262N-AF680$485 / 100μlE45R18262N-AF700$485 / 100μlE45R18262N-AF750$485 / 100μlE45R18262N-AF790$485 / 100μlE45R18262N-APC$485 / 100μlE45R18262N-PE$485 / 100μlE45R18262N-Cy3$485 / 100μlE45R18262N-Cy5$485 / 100μlE45R18262N-Cy5.5$485 / 100μlE45R18262N-Cy7$485 / 100μlE45R18262N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

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LAPTM4B Rabbit pAb | EnoGene Biotech Co. Ltd