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CPSF4 Rabbit pAb

Human
O95639
$409/ 100 µl
Quantity
Total: $409

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5506932
TypePolyclonal Antibodies
HostRabbit
Positive controlHeLa, Jurkat, 22Rv1
IsotypeIgG
SummaryInhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain. The NS1 effector domain functionally interacts with the cellular 30 kDa subunit of cleavage and polyadenylation specific factor 4, an essential component of the 3' end processing machinery of cellular pre-mRNAs. In influenza virus-infected cells, the NS1 protein is physically associated with cleavage and polyadenylation specific factor 4, 30kD subunit. Binding of the NS1 protein to the 30 kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end cleavage and polyadenylation of host pre-mRNAs. Thus the NS1 protein selectively inhibits the nuclear export of cellular, and not viral, mRNAs. Multiple alternatively spliced transcript variants that encode different isoforms have been described for this gene.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-244 of human CPSF4 (NP_001075028.1).
PurificationAffinity purification
Gene ID10898
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:1000 - 1:2000

All Names

AlternameCPSF4; CPSF30; NAR; NEB-1; NEB1

Conjugated Antibody

This product is also available conjugated. Format: E45R17908N-Conjugate. Price: $485 / Size: 100μl.

E45R17908N-FITC$485 / 100μlE45R17908N-Biotin$485 / 100μlE45R17908N-HRP$485 / 100μlE45R17908N-AP$485 / 100μlE45R17908N-AF350$485 / 100μlE45R17908N-AF405M$485 / 100μlE45R17908N-AF488$485 / 100μlE45R17908N-AF514$485 / 100μlE45R17908N-AF532$485 / 100μlE45R17908N-AF555$485 / 100μlE45R17908N-AF568$485 / 100μlE45R17908N-AF405S$485 / 100μlE45R17908N-AF405L$485 / 100μlE45R17908N-AF546$485 / 100μlE45R17908N-AF594$485 / 100μlE45R17908N-AF610$485 / 100μlE45R17908N-AF635$485 / 100μlE45R17908N-AF647$485 / 100μlE45R17908N-AF680$485 / 100μlE45R17908N-AF700$485 / 100μlE45R17908N-AF750$485 / 100μlE45R17908N-AF790$485 / 100μlE45R17908N-APC$485 / 100μlE45R17908N-PE$485 / 100μlE45R17908N-Cy3$485 / 100μlE45R17908N-Cy5$485 / 100μlE45R17908N-Cy5.5$485 / 100μlE45R17908N-Cy7$485 / 100μlE45R17908N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

CPSF4 Rabbit pAb | EnoGene Biotech Co. Ltd