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KIR3DL2 Rabbit pAb
Human, Mouse, Rat
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5506817
TypePolyclonal Antibodies
HostRabbit
Positive controlHL-60, LO2, MCF7, Mouse spleen, Mouse liver, Rat spleen
IsotypeIgG
SummaryKiller cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. This gene is one of the 'framework' loci that is present on all haplotypes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 361-455 of human KIR3DL2 (NP_006728.2).
PurificationAffinity purification
Gene ID3812
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:2000
All Names
AlternameKIR3DL2; 3DL2; CD158K; KIR-3DL2; NKAT-4; NKAT4; NKAT4B; p140
Conjugated Antibody
This product is also available conjugated. Format: E45R17746N-Conjugate. Price: $485 / Size: 100μl.
E45R17746N-FITC$485 / 100μlE45R17746N-Biotin$485 / 100μlE45R17746N-HRP$485 / 100μlE45R17746N-AP$485 / 100μlE45R17746N-AF350$485 / 100μlE45R17746N-AF405M$485 / 100μlE45R17746N-AF488$485 / 100μlE45R17746N-AF514$485 / 100μlE45R17746N-AF532$485 / 100μlE45R17746N-AF555$485 / 100μlE45R17746N-AF568$485 / 100μlE45R17746N-AF405S$485 / 100μlE45R17746N-AF405L$485 / 100μlE45R17746N-AF546$485 / 100μlE45R17746N-AF594$485 / 100μlE45R17746N-AF610$485 / 100μlE45R17746N-AF635$485 / 100μlE45R17746N-AF647$485 / 100μlE45R17746N-AF680$485 / 100μlE45R17746N-AF700$485 / 100μlE45R17746N-AF750$485 / 100μlE45R17746N-AF790$485 / 100μlE45R17746N-APC$485 / 100μlE45R17746N-PE$485 / 100μlE45R17746N-Cy3$485 / 100μlE45R17746N-Cy5$485 / 100μlE45R17746N-Cy5.5$485 / 100μlE45R17746N-Cy7$485 / 100μlE45R17746N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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