World supplier of antibodies, antigens and kits since 2007
Other Products
GP1BB Rabbit pAb
Human, Mouse, Rat
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5506815
TypePolyclonal Antibodies
HostRabbit
Positive controlLO2, THP-1, Mouse heart, Mouse brain, Rat brain
IsotypeIgG
SummaryPlatelet glycoprotein Ib (GPIb) is a heterodimeric transmembrane protein consisting of a disulfide-linked 140 kD alpha chain and 22 kD beta chain. It is part of the GPIb-V-IX system that constitutes the receptor for von Willebrand factor (VWF), and mediates platelet adhesion in the arterial circulation. GPIb alpha chain provides the VWF binding site, and GPIb beta contributes to surface expression of the receptor and participates in transmembrane signaling through phosphorylation of its intracellular domain. Mutations in the GPIb beta subunit have been associated with Bernard-Soulier syndrome, velocardiofacial syndrome and giant platelet disorder. The 206 amino acid precursor of GPIb beta is synthesized from a 1.0 kb mRNA expressed in plateletes and megakaryocytes. A 411 amino acid protein arising from a longer, unspliced transcript in endothelial cells has been described; however, the authenticity of this product has been questioned. Yet another less abundant GPIb beta mRNA species of 3.5 kb, expressed in nonhematopoietic tissues such as endothelium, brain and heart, was shown to result from inefficient usage of a non-consensus polyA signal in the neighboring upstream gene (SEPT5, septin 5). In the absence of polyadenylation from its own imperfect site, the SEPT5 gene produces read-through transcripts that use the consensus polyA signal of this gene.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 27-147 of human GP1BB (NP_000398.1).
PurificationAffinity purification
Gene ID2812
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:200 - 1:1000
All Names
AlternameGP1BB; BDPLT1; BS; CD42C; GPIBB; GPIbbeta
Conjugated Antibody
This product is also available conjugated. Format: E45R17742N-Conjugate. Price: $485 / Size: 100μl.
E45R17742N-FITC$485 / 100μlE45R17742N-Biotin$485 / 100μlE45R17742N-HRP$485 / 100μlE45R17742N-AP$485 / 100μlE45R17742N-AF350$485 / 100μlE45R17742N-AF405M$485 / 100μlE45R17742N-AF488$485 / 100μlE45R17742N-AF514$485 / 100μlE45R17742N-AF532$485 / 100μlE45R17742N-AF555$485 / 100μlE45R17742N-AF568$485 / 100μlE45R17742N-AF405S$485 / 100μlE45R17742N-AF405L$485 / 100μlE45R17742N-AF546$485 / 100μlE45R17742N-AF594$485 / 100μlE45R17742N-AF610$485 / 100μlE45R17742N-AF635$485 / 100μlE45R17742N-AF647$485 / 100μlE45R17742N-AF680$485 / 100μlE45R17742N-AF700$485 / 100μlE45R17742N-AF750$485 / 100μlE45R17742N-AF790$485 / 100μlE45R17742N-APC$485 / 100μlE45R17742N-PE$485 / 100μlE45R17742N-Cy3$485 / 100μlE45R17742N-Cy5$485 / 100μlE45R17742N-Cy5.5$485 / 100μlE45R17742N-Cy7$485 / 100μlE45R17742N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
Categories by research area
Categories by product type
- Antibodies
- Primary Antibodies
- Tag antibodies
- Internal control antibodies
- Pathological (Immunohistochemistry, IHC) antibodies
- Cell Signal Transduction Research Antibodies
- Secondary Antibody
- Antibody Sampler Kits
- ELISA Kits
- Recombinant Proteins
- Fluorescence Reagents
- Signal Inhibitors and Activators
- Transfection Reagent
- Cell biology kits
- Overexpression Cell Lines
- Cell Lysates
- Purification Resins
- 2019-nCoV & Monkeypox