World supplier of antibodies, antigens and kits since 2007

Welcome, Sign in or Register

My Cart(0)
Other Products

NPC1L1 Rabbit pAb

E45R17684NDatasheetCOAMSDS
Human
Q9UHC9
$409/ 100 µl
Quantity
Total: $409

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Cite ID#EN5506858
TypePolyclonal Antibodies
HostRabbit
Positive controlHepG2, 293T, K-562
IsotypeIgG
SummaryThe protein encoded by this gene is a multi-pass membrane protein. It contains a conserved N-terminal Niemann-Pick C1 (NPC1) domain and a putative sterol-sensing domain (SSD) which includes a YQRL motif functioning as a plasma membrane to trans-Golgi network transport signal in other proteins. This protein takes up free cholesterol into cells through vesicular endocytosis and plays a critical role in the absorption of intestinal cholesterol. It also has the ability to transport alpha-tocopherol (vitamin E). The drug ezetimibe targets this protein and inhibits the absorption of intestinal cholesterol and alpha-tocopherol. In addition, this protein may play a critical role in regulating lipid metabolism. Polymorphic variations in this gene are associated with plasma total cholesterol and low-density lipoprotein cholesterol (LDL-C) levels and coronary heart disease (CHD) risk. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1030-1100 of human NPC1L1 (NP_001095118.1).
PurificationAffinity purification
Gene ID29881
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:1000 - 1:4000

All Names

AlternameNPC1L1; NPC11L1
📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Certificate of Analysis (PDF)🧪MSDS
Material safety data sheet (PDF)

Conjugated Antibody

This product is also available conjugated. Format: E45R17684N-Conjugate. Price: $485 / Size: 100μl.

E45R17684N-FITC$485 / 100μlE45R17684N-Biotin$485 / 100μlE45R17684N-HRP$485 / 100μlE45R17684N-AP$485 / 100μlE45R17684N-AF350$485 / 100μlE45R17684N-AF405M$485 / 100μlE45R17684N-AF488$485 / 100μlE45R17684N-AF514$485 / 100μlE45R17684N-AF532$485 / 100μlE45R17684N-AF555$485 / 100μlE45R17684N-AF568$485 / 100μlE45R17684N-AF405S$485 / 100μlE45R17684N-AF405L$485 / 100μlE45R17684N-AF546$485 / 100μlE45R17684N-AF594$485 / 100μlE45R17684N-AF610$485 / 100μlE45R17684N-AF635$485 / 100μlE45R17684N-AF647$485 / 100μlE45R17684N-AF680$485 / 100μlE45R17684N-AF700$485 / 100μlE45R17684N-AF750$485 / 100μlE45R17684N-AF790$485 / 100μlE45R17684N-APC$485 / 100μlE45R17684N-PE$485 / 100μlE45R17684N-Cy3$485 / 100μlE45R17684N-Cy5$485 / 100μlE45R17684N-Cy5.5$485 / 100μlE45R17684N-Cy7$485 / 100μlE45R17684N-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

Related Products

RASH/RASK/RASN AntibodyRASH/RASK/RASN AntibodyE11-0313,$225SHIP AntibodySHIP AntibodyE11-0320,$225Syk AntibodySyk AntibodyE11-0332,$225CTRO AntibodyCTRO AntibodyE11-10038,$225TUSC2 AntibodyTUSC2 AntibodyE11-10196,$225
NPC1L1 Rabbit pAb | EnoGene Biotech Co. Ltd