World supplier of antibodies, antigens and kits since 2007
Other Products
SFPQ Rabbit pAb
$409/ 100 µl
QuantityTotal: $409
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Cite ID#EN5516504
TypePolyclonal Antibodies
HostRabbit
Positive controlOVCAR3, HeLa, Jurkat, HepG2, Mouse brain, Mouse liver, Mouse spleen, Rat brain
IsotypeIgG
SummaryDNA- and RNA binding protein, involved in several nuclear processes. Essential pre-mRNA splicing factor required early in spliceosome formation and for splicing catalytic step II, probably as a heteromer with NONO. Binds to pre-mRNA in spliceosome C complex, and specifically binds to intronic polypyrimidine tracts. Involved in regulation of signal-induced alternative splicing. SFPQ is involved in transcriptional regulation. Functions as transcriptional activator (PubMed:25765647). Transcriptional repression is mediated by an interaction of SFPQ with SIN3A and subsequent recruitment of histone deacetylases (HDACs). The SFPQ-NONO-NR5A1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional activity. SFPQ isoform Long binds to the DNA binding domains (DBD) of nuclear hormone receptors, like RXRA and probably THRA, and acts as transcriptional corepressor in absence of hormone ligands. Binds the DNA sequence 5'-CTGAGTC-3' in the insulin-like growth factor response element (IGFRE) and inhibits IGF-I-stimulated transcriptional activity. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Required for the assembly of nuclear speckles (PubMed:25765647). Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex.
FormLiquid
Storage BufferBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Price409$
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 578-707 of human SFPQ (NP_005057.1).
PurificationAffinity purification
Gene ID6421
Storage/StabilityStore at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
DilutionWB 1:500 - 1:1000
IHC 1:50 - 1:100
IF 1:50 - 1:100
IP 1:50 - 1:100
IHC 1:50 - 1:100
IF 1:50 - 1:100
IP 1:50 - 1:100
All Names
AlternameSFPQ; POMP100; PPP1R140; PSF
Conjugated Antibody
This product is also available conjugated. Format: E45R17600N-Conjugate. Price: $485 / Size: 100μl.
E45R17600N-FITC$485 / 100μlE45R17600N-Biotin$485 / 100μlE45R17600N-HRP$485 / 100μlE45R17600N-AP$485 / 100μlE45R17600N-AF350$485 / 100μlE45R17600N-AF405M$485 / 100μlE45R17600N-AF488$485 / 100μlE45R17600N-AF514$485 / 100μlE45R17600N-AF532$485 / 100μlE45R17600N-AF555$485 / 100μlE45R17600N-AF568$485 / 100μlE45R17600N-AF405S$485 / 100μlE45R17600N-AF405L$485 / 100μlE45R17600N-AF546$485 / 100μlE45R17600N-AF594$485 / 100μlE45R17600N-AF610$485 / 100μlE45R17600N-AF635$485 / 100μlE45R17600N-AF647$485 / 100μlE45R17600N-AF680$485 / 100μlE45R17600N-AF700$485 / 100μlE45R17600N-AF750$485 / 100μlE45R17600N-AF790$485 / 100μlE45R17600N-APC$485 / 100μlE45R17600N-PE$485 / 100μlE45R17600N-Cy3$485 / 100μlE45R17600N-Cy5$485 / 100μlE45R17600N-Cy5.5$485 / 100μlE45R17600N-Cy7$485 / 100μlE45R17600N-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
Categories by research area
Categories by product type
- Antibodies
- Primary Antibodies
- Tag antibodies
- Internal control antibodies
- Pathological (Immunohistochemistry, IHC) antibodies
- Cell Signal Transduction Research Antibodies
- Secondary Antibody
- Antibody Sampler Kits
- ELISA Kits
- Recombinant Proteins
- Fluorescence Reagents
- Signal Inhibitors and Activators
- Transfection Reagent
- Cell biology kits
- Overexpression Cell Lines
- Cell Lysates
- Purification Resins
- 2019-nCoV & Monkeypox